ABCB11

Gene Name		ATP-binding cassette, sub-family B (MDR/TAP), member 11
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Apical Part Of Cell Intercellular Canaliculus Extracellular Vesicular Exosome
	Molecular Function	Transporter Activity ATP Binding Sodium-exporting ATPase Activity, Phosphorylative Mechanism Canalicular Bile Acid Transmembrane Transporter Activity Bile Acid-exporting ATPase Activity ATPase Activity, Coupled To Transmembrane Movement Of Substances
	Biological Process	Bile Acid Biosynthetic Process Transport Bile Acid Metabolic Process Bile Acid And Bile Salt Transport Canalicular Bile Acid Transport Sodium Ion Transmembrane Transport Small Molecule Metabolic Process Transmembrane Transport
Pathways		Bile acid and bile salt metabolism Metabolism of lipids and lipoproteins Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol Recycling of bile acids and salts Synthesis of bile acids and bile salts
Drugs		Adenosine triphosphate Glyburide
Diseases
GWAS		Fasting plasma glucose ( 18521185) Glycated hemoglobin levels ( 20858683) Liver enzyme levels (alkaline phosphatase) ( 22001757) Metabolic syndrome (bivariate traits) ( 21386085) Metabolic traits ( 19060910) Metabolite levels ( 21909109)
Protein-protein Interactions		3 interactors: HAX1 LY6D NR4A1
Entrez ID		8647
HPRD ID		04436
Ensembl ID		ENSG00000073734
Uniprot IDs		O95342
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?		1b1 3a4 abcc2 abcg2 ambrisentan bosentan calcein cyp2c19 cyp3a4 desmethyl endothelin fluorescein geometric gp hek hydroxy hydroxylated hydroxymethyl ls180 mdr1 oatp oatp1b1 oatp1b3 p450 perpetrators pharmacokinetic pregnane transporting