PKIB and KRTAP3-1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PKIB	KRTAP3-1
Description		cAMP-dependent protein kinase inhibitor beta	keratin associated protein 3-1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Protein Kinase Inhibitor Activity CAMP-dependent Protein Kinase Inhibitor Activity Protein Binding	Structural Molecule Activity Protein Binding
	Biological Process	Positive Regulation Of Telomere Maintenance
Pathways			Keratinization
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494) White blood cell count ( 32888494)
Interacting Genes		9 interacting genes: DYNLL1 E2F1 E2F3 KRTAP3-1 LY6D NLGN3 PIN1 PRKACA PRKACB	83 interacting genes: ADAM12 AGXT ANAPC11 BMP7 CDKN1A CELA2B CERK CFP CIMIP1 CNNM3 CREB5 CTRC CYSRT1 DMRT3 DOCK2 FAM168A FAM222B FOXH1 FRS3 GATA2 GNE GPS2 GSTP1 HCK HEY2 HOXB9 HR HSF4 IL16 ITGB4 KRTAP10-8 KRTAP13-2 KRTAP13-3 KRTAP15-1 KRTAP26-1 KRTAP4-11 KRTAP4-12 KRTAP6-1 KRTAP9-3 KRTAP9-8 LCE1B LCE2B LCE3A LCE3D LCE4A LCE5A LMO4 LRRC41 MAPKBP1 MRPL40 MYPOP NOTCH2NLA NTAQ1 OTX1 PATZ1 PCSK5 PHLDA1 PKIB PLSCR4 POLR1C PTPMT1 PVR RBPMS RECK REEP6 RNF44 SAMD7 SAXO4 SLC5A5 SMARCC1 SPAG8 SPMIP9 TEKT3 TLX3 TNS2 VASN VENTX VGLL3 WDR25 YPEL3 ZFHX2 ZNF414 ZNF446
Entrez ID		5570	83896
HPRD ID		06075	13937
Ensembl ID		ENSG00000135549	ENSG00000212901
Uniprot IDs		Q9C010	Q9BYR8
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Fat Cell Proliferation CAMP-dependent Protein Kinase Complex CAMP-dependent Protein Kinase Activity High-density Lipoprotein Particle Assembly Vascular Endothelial Cell Response To Laminar Fluid Shear Stress Vascular Endothelial Cell Response To Fluid Shear Stress Cellular Response To Laminar Fluid Shear Stress Renal Water Homeostasis DNA-binding Transcription Activator Activity Response To Laminar Fluid Shear Stress Plasma Lipoprotein Particle Assembly Protein-lipid Complex Assembly Multicellular Organismal-level Water Homeostasis Cellular Response To Fluid Shear Stress Negative Regulation Of Smoothened Signaling Pathway Centrosome Ciliary Base Response To Fluid Shear Stress Regulation Of Protein Processing Regulation Of Protein Maturation Cis-trans Isomerase Activity Negative Regulation Of TORC1 Signaling TORC1 Signaling Cellular Response To Stress Multicellular Organismal-level Chemical Homeostasis Scaffold Protein Binding Regulation Of Biological Quality Negative Regulation Of Catabolic Process Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Smoothened Signaling Pathway TOR Signaling Positive Regulation Of Insulin Secretion Neural Tube Closure Negative Regulation Of TOR Signaling Tube Closure Negative Regulation Of DNA Strand Resection Involved In Replication Fork Processing Regulation Of TORC1 Signaling Protein Peptidyl-prolyl Isomerization Phosphothreonine Residue Binding Positive Regulation Of Peptide Hormone Secretion Positive Regulation Of Peptide Secretion Deoxyribonuclease Inhibitor Activity Regulation Of DNA Strand Resection Involved In Replication Fork Processing Nitric-oxide Synthase Inhibitor Activity Rhythmic Synaptic Transmission Symmetric, GABA-ergic, Inhibitory Synapse Renal System Process Lens Fiber Cell Apoptotic Process RNA Polymerase II Transcription Regulator Complex Tube Formation	Intermediate Filament Protein Binding Keratinization Keratin Filament Epidermis Development Axonemal A Tubule Inner Sheath Tissue Development Ventral Spinal Cord Interneuron Differentiation Heart Trabecula Morphogenesis Cellular Response To Cell-matrix Adhesion
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