SCARF1 and LCE1D

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SCARF1	LCE1D
Description		scavenger receptor class F member 1	late cornified envelope 1D
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Endocytic Vesicle Membrane	Cornified Envelope Cytoplasm Perinuclear Region Of Cytoplasm
	Molecular Function	Transmembrane Signaling Receptor Activity Scavenger Receptor Activity Protein Binding Low-density Lipoprotein Particle Binding	Protein Binding Identical Protein Binding
	Biological Process	Cholesterol Catabolic Process Receptor-mediated Endocytosis Cell Adhesion Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Positive Regulation Of Neuron Projection Development Neuron Remodeling Dendrite Development Positive Regulation Of Axon Regeneration	Epidermis Development Keratinization Cognition Cellular Response To Calcium Ion
Pathways		Scavenging by Class F Receptors Scavenging by Class F Receptors	Formation of the cornified envelope
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Intracranial aneurysm ( 30823506) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)
Interacting Genes		22 interacting genes: CALR CLDN7 COQ9 CREB3L1 CYSRT1 FAM209A GJA8 GPR37L1 GPX8 HSD17B13 KCNJ6 KRTAP1-1 KRTAP10-8 KRTAP5-7 LCE1D LHFPL2 MEOX2 MRM3 NEMP1 SCARF2 SLC7A14 TGM1	69 interacting genes: ADAMTSL4 ALPP AMOT CATSPER1 CHIC2 CRCT1 CYP21A2 CYSRT1 FBLN1 GRN HOXA1 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1B LCE1C LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3B LCE4A LCE5A MACO1 MDFI MEOX2 NBPF19 NOTCH2NLA NTAQ1 NUFIP2 PCSK5 PIAS4 RAD54L2 RGS17 RGS20 RNF4 SCARF1 SMCP SPRY1 TGFB1 TRIM42 UBE2I
Entrez ID		8578	353134
HPRD ID		06386	13968
Ensembl ID		ENSG00000074660	ENSG00000172155
Uniprot IDs		A8K6Z5 Q14162	Q5T752
PDB IDs		8HN0 8HNA
Enriched GO Terms of Interacting Partners?		Cornified Envelope	Intermediate Filament Keratin Filament Epidermis Development Keratinization Hair Cycle Tissue Development Identical Protein Binding Protein Binding Negative Regulation Of Protein Localization To Chromatin
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