SCARF1 and SCARF2

Number of citations of the paper that reports this interaction (PMID 12154095)
9

Data Source:
HPRD (in vitro)

		SCARF1	SCARF2
Gene Name		scavenger receptor class F, member 1	scavenger receptor class F, member 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Endocytic Vesicle Membrane	Focal Adhesion Integral Component Of Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Scavenger Receptor Activity Low-density Lipoprotein Particle Binding	Scavenger Receptor Activity Protein Binding
	Biological Process	Cholesterol Catabolic Process Receptor-mediated Endocytosis Cell Adhesion Signal Transduction Positive Regulation Of Neuron Projection Development Neuron Remodeling Dendrite Development Positive Regulation Of Axon Regeneration	Receptor-mediated Endocytosis Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules
Pathways		Scavenging by Class F Receptors
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: CALR SCARF2	1 interactors: SCARF1
Entrez ID		8578	91179
HPRD ID		06386	15299
Ensembl ID		ENSG00000074660	ENSG00000244486
Uniprot IDs		A8K6Z5 Q14162	Q96GP6
PDB IDs
Enriched GO Terms of Interacting Partners?		Peptide Antigen Assembly With MHC Class I Protein Complex Receptor-mediated Endocytosis Sequestering Of Calcium Ion Positive Regulation Of Dendritic Cell Chemotaxis Glucocorticoid Receptor Signaling Pathway Endocytosis Sequestering Of Metal Ion Protein Maturation By Protein Folding Cellular Response To Lithium Ion Cortical Actin Cytoskeleton Organization Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Cortical Cytoskeleton Organization Response To Lithium Ion Cellular Senescence Regulation Of Substrate Adhesion-dependent Cell Spreading Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Response To Testosterone Protein Export From Nucleus Protein Maturation Regulation Of Meiosis Negative Regulation Of Retinoic Acid Receptor Signaling Pathway Vesicle-mediated Transport Positive Regulation Of Phagocytosis Regulation Of Retinoic Acid Receptor Signaling Pathway Regulation Of Meiotic Cell Cycle Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Positive Regulation Of Nuclease Activity Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Chaperone-mediated Protein Folding Regulation Of Phagocytosis Positive Regulation Of Leukocyte Chemotaxis Positive Regulation Of DNA Replication Intracellular Steroid Hormone Receptor Signaling Pathway Cell Aging	Neuron Remodeling Positive Regulation Of Axon Regeneration Cholesterol Catabolic Process Positive Regulation Of Neuron Projection Regeneration Regulation Of Axon Regeneration Steroid Catabolic Process Neuron Maturation Alcohol Catabolic Process Cholesterol Metabolic Process Sterol Metabolic Process Dendrite Development Cell Maturation Positive Regulation Of Neuron Projection Development Lipid Catabolic Process Steroid Metabolic Process Positive Regulation Of Cell Projection Organization Positive Regulation Of Neuron Differentiation Alcohol Metabolic Process Receptor-mediated Endocytosis
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