SCARF1 and GPR37L1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SCARF1	GPR37L1
Description		scavenger receptor class F member 1	G protein-coupled receptor 37 like 1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Endocytic Vesicle Membrane	Plasma Membrane Membrane Cell Projection Receptor Complex Ciliary Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Scavenger Receptor Activity Protein Binding Low-density Lipoprotein Particle Binding	G Protein-coupled Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Prosaposin Receptor Activity Peptide Binding
	Biological Process	Cholesterol Catabolic Process Receptor-mediated Endocytosis Cell Adhesion Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Positive Regulation Of Neuron Projection Development Neuron Remodeling Dendrite Development Positive Regulation Of Axon Regeneration	Negative Regulation Of Systemic Arterial Blood Pressure Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Smoothened Signaling Pathway Positive Regulation Of Cerebellar Granule Cell Precursor Proliferation Cellular Response To Reactive Oxygen Species Positive Regulation Of MAPK Cascade Negative Regulation Of Neuron Differentiation Negative Regulation Of Smoothened Signaling Pathway Negative Regulation Of Astrocyte Differentiation Bergmann Glial Cell Differentiation
Pathways		Scavenging by Class F Receptors Scavenging by Class F Receptors	Peptide ligand-binding receptors G alpha (i) signalling events
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Intracranial aneurysm ( 30823506) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Age at first sexual intercourse ( 27089180) Diverticular disease ( 30177863)
Interacting Genes		22 interacting genes: CALR CLDN7 COQ9 CREB3L1 CYSRT1 FAM209A GJA8 GPR37L1 GPX8 HSD17B13 KCNJ6 KRTAP1-1 KRTAP10-8 KRTAP5-7 LCE1D LHFPL2 MEOX2 MRM3 NEMP1 SCARF2 SLC7A14 TGM1	53 interacting genes: ADGRB3 AQP1 AQP10 ARL13B CD46 CISD2 CLDN7 CLDND2 CLEC2A CREB3L1 CYB561A3 DYRK1A ELOVL4 ERG28 FAM209A FFAR2 FXYD3 FXYD6-FXYD2 GPR152 GPR42 GPX8 IGFBP5 INSIG2 JAGN1 LHFPL5 PDCD1LG2 PLN PRH1 RNF122 RPRM SCARB2 SCARF1 SEC22A SERP1 SLC30A8 STOM SYNPR THAP4 THSD7B TM4SF4 TMEM147 TMEM243 TMEM248 TMEM52B TMEM54 TMEM80 TMEM86A TMEM86B TMEM97 TNFRSF10C TSPAN12 UNC93B1 UPK1B
Entrez ID		8578	9283
HPRD ID		06386	13603
Ensembl ID		ENSG00000074660	ENSG00000170075
Uniprot IDs		A8K6Z5 Q14162	O60883
PDB IDs		8HN0 8HNA
Enriched GO Terms of Interacting Partners?		Cornified Envelope	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Alkenylglycerophosphocholine Hydrolase Activity Protein Binding Peptide Hormone Secretion Amide Transport Peptide Secretion Hormone Secretion Glycerol Transmembrane Transport Peptide Transport Hormone Transport Polyol Transmembrane Transport Insulin Secretion
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