GFM1 and TRIM55

Number of citations of the paper that reports this interaction (PMID 18157088)
41

Data Source:
BioGRID (two hybrid, pull down)

		GFM1	TRIM55
Gene Name		G elongation factor, mitochondrial 1	tripartite motif containing 55
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrial Matrix	Nucleus Cytoplasm Microtubule
	Molecular Function	Translation Elongation Factor Activity GTPase Activity Protein Binding GTP Binding Poly(A) RNA Binding	Signal Transducer Activity Zinc Ion Binding Identical Protein Binding
	Biological Process	Organelle Organization Mitochondrial Translation Mitochondrial Translational Elongation	Signal Transduction
Pathways		Mitochondrial translation Organelle biogenesis and maintenance Mitochondrial translation elongation
Drugs
Diseases
GWAS			Response to statin therapy ( 22666496)
Protein-Protein Interactions		2 interactors: TRIM55 TRIM63	61 interactors: ACTA1 ANKRD1 ATP5B ATXN3 ATXN3L BRAP CKM DCAF6 DES EEF1G EHHADH EIF3E ESPL1 FHL2 FLNA FLNB FLNC GFM1 GMEB1 LMCD1 MDM4 MRPL19 MRPL41 MYBPC1 MYBPC3 MYOT MYOZ1 NDUFA1 NEB NEBL NOMO1 OTUB1 OTUB2 PCGF1 PIAS1 PIAS2 PIAS3 RNF114 SQSTM1 STAM TCAP TNNI1 TNNI2 TNNI3 TRIM27 TRIM54 TRIM63 TTN UBE2D1 UBE2D2 UBE2D3 UCHL3 UCHL5 USP13 USP28 USP4 USP5 USP7 USP8 UXT YOD1
Entrez ID		85476	84675
HPRD ID		07365	05927
Ensembl ID		ENSG00000168827	ENSG00000147573
Uniprot IDs		E5KND5 Q96RP9	Q9BYV6
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Skeletal Muscle Atrophy Striated Muscle Atrophy Muscle Atrophy Skeletal Muscle Adaptation Cellular Response To Dexamethasone Stimulus Response To Dexamethasone Response To Electrical Stimulus Cellular Response To Glucocorticoid Stimulus Cellular Response To Corticosteroid Stimulus Response To Interleukin-1	Actin-myosin Filament Sliding Muscle Filament Sliding Actin-mediated Cell Contraction Protein Deubiquitination Protein Modification By Small Protein Removal Actin Filament-based Movement Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Muscle Contraction Actin Filament-based Process Cellular Protein Catabolic Process Protein Catabolic Process Muscle System Process Protein K48-linked Deubiquitination Cellular Macromolecule Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Catabolic Process Striated Muscle Cell Development Cellular Protein Metabolic Process Muscle Structure Development Muscle Cell Development Protein K63-linked Deubiquitination Myofibril Assembly Proteolysis Cellular Protein Modification Process Striated Muscle Tissue Development Cardiac Muscle Tissue Morphogenesis Striated Muscle Cell Differentiation Muscle Tissue Development Muscle Tissue Morphogenesis Actomyosin Structure Organization Muscle Organ Morphogenesis Cardiac Muscle Tissue Development Protein Metabolic Process Muscle Organ Development Protein Modification By Small Protein Conjugation Muscle Cell Differentiation Myosin Filament Assembly Catabolic Process Actin Cytoskeleton Organization Skeletal Muscle Thin Filament Assembly Cytoskeleton Organization Skeletal Myofibril Assembly Response To Muscle Stretch Heart Morphogenesis Striated Muscle Contraction Cellular Process
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