YBX3 and NFYB

Number of citations of the paper that reports this interaction (PMID 9442396)
1

Data Source:
HPRD (in vitro)

		YBX3	NFYB
Gene Name		Y box binding protein 3	nuclear transcription factor Y, beta
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Polysome Tight Junction Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm CCAAT-binding Factor Complex Protein-DNA Complex
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Double-stranded DNA Binding Single-stranded DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity MRNA 3'-UTR Binding Rho GTPase Binding Poly(A) RNA Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Complex Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity Repressing Transcription Factor Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter In Utero Embryonic Development Transcription, DNA-templated Spermatogenesis Male Gonad Development Response To Cold Fertilization Positive Regulation Of Organ Growth Negative Regulation Of Skeletal Muscle Tissue Development Negative Regulation Of Necroptotic Process 3'-UTR-mediated MRNA Stabilization Cellular Response To Tumor Necrosis Factor Cellular Hyperosmotic Response Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress Positive Regulation Of Cytoplasmic Translation	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cellular Lipid Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Transcription, DNA-templated
Pathways			PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins ATF4 activates genes ATF6-alpha activates chaperone genes Regulation of cholesterol biosynthesis by SREBP (SREBF) Activation of gene expression by SREBF (SREBP) Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) PERK regulates gene expression ATF6-alpha activates chaperones Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: GSK3B IL7R MAPK1 NFYB PCBP2 RALA TJP1 VEGFA	24 interactors: AGTRAP C1QBP CEBPZ CIITA CNTN2 DRAP1 ELF1 EP300 GRB2 MAOB MYC NFYA NFYC POLE4 SMYD3 SP1 TAF11 TAF12 TAF6 TBP TP53 TP73 YBX1 YBX3
Entrez ID		8531	4801
HPRD ID		10347	01794
Ensembl ID		ENSG00000060138	ENSG00000120837
Uniprot IDs		P16989	P25208
PDB IDs			1N1J 4AWL
Enriched GO Terms of Interacting Partners?		Response To External Stimulus Cellular Response To Organic Substance Regulation Of Cell Size Positive Regulation Of Peptidyl-threonine Phosphorylation Cellular Response To Growth Factor Stimulus Regulation Of Immune System Process Chemotaxis Response To Growth Factor Response To Organic Substance Neurotrophin TRK Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cellular Response To Heat Regulation Of Vascular Permeability Neurotrophin Signaling Pathway Positive Regulation Of Gene Expression Response To Biotic Stimulus Positive Regulation Of Axon Extension Positive Regulation Of Cell Projection Organization Regulation Of MAP Kinase Activity Positive Regulation Of Cellular Component Biogenesis Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Cellular Component Size Positive Regulation Of Cell-matrix Adhesion Apoptotic Process Positive Regulation Of Cell Adhesion Programmed Cell Death Regulation Of Vesicle-mediated Transport Cellular Response To Heat Regulation Of Cellular Localization Axon Guidance Cell Death Death Cell Morphogenesis Regulation Of Axon Extension Regulation Of Cellular Amino Acid Metabolic Process Response To Abiotic Stimulus Immune System Process Positive Regulation Of Axonogenesis Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Protein Kinase D Signaling Cell-cell Signaling Involved In Cell-cell Junction Organization Basophil Chemotaxis Regulation Of Cell Projection Organization Locomotion Anatomical Structure Morphogenesis Regulation Of Cellular Ketone Metabolic Process Vascular Endothelial Growth Factor Receptor Signaling Pathway In Utero Embryonic Development Immune Response Regulation Of Peptidyl-serine Phosphorylation	Positive Regulation Of Macromolecule Biosynthetic Process Transcription, DNA-templated Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Cellular Aromatic Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Viral Process Cellular Nitrogen Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Cellular Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process DNA-templated Transcription, Initiation Positive Regulation By Host Of Viral Transcription Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Transcription Elongation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Regulation Of Cellular Process Negative Regulation Of Cellular Metabolic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Interaction With Symbiont Negative Regulation Of Signal Transduction Cellular Response To Radiation Negative Regulation Of Signaling Response To Ionizing Radiation Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Tagcloud ?		absent alleles aml atlas australasian bank box conjunction enrichment epigenetic frequently hnrnpr hypermethylation leukemic marks matr3 promoter sf3a1 sf3b1 silence silico somatic splicing srsf2 suppressing u2af1 u937 zfr zrsr2	attenuates behave caf ccaat competes concordance conversely counteracts deacetylase deltanp73 deltanp73alpha detecting exist hdac hdac1 immunofluorescence motif nih3t3 p73 p73alpha pdgfrb periods repression starved supporting tap73 trichostatin yc
Tagcloud (Difference) ?		absent alleles aml atlas australasian bank box conjunction enrichment epigenetic frequently hnrnpr hypermethylation leukemic marks matr3 promoter sf3a1 sf3b1 silence silico somatic splicing srsf2 suppressing u2af1 u937 zfr zrsr2	attenuates behave caf ccaat competes concordance conversely counteracts deacetylase deltanp73 deltanp73alpha detecting exist hdac hdac1 immunofluorescence motif nih3t3 p73 p73alpha pdgfrb periods repression starved supporting tap73 trichostatin yc
Tagcloud (Intersection) ?