MMP23B and GLRX

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		MMP23B	GLRX
Gene Name		matrix metallopeptidase 23B	glutaredoxin (thioltransferase)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Proteinaceous Extracellular Matrix Intracellular Endoplasmic Reticulum Membrane Integral Component Of Membrane	Nucleus Mitochondrion Cytosol Extracellular Vesicular Exosome
	Molecular Function	Metalloendopeptidase Activity Metallopeptidase Activity Zinc Ion Binding	Electron Carrier Activity Glutathione Disulfide Oxidoreductase Activity Protein N-terminus Binding Glutathione Oxidoreductase Activity
	Biological Process	Reproduction Proteolysis	Nucleobase-containing Small Molecule Interconversion Small Molecule Metabolic Process Cell Redox Homeostasis Positive Regulation Of Membrane Potential Nucleobase-containing Small Molecule Metabolic Process Oxidation-reduction Process Protein Deglutathionylation Positive Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways			Metabolism of nucleotides Synthesis and interconversion of nucleotide di- and triphosphates
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: GLRX	7 interactors: AQP5 CASP3 GOT2 MAP3K5 MMP23B NFIC PTPN1
Entrez ID		8510	2745
HPRD ID		04503	02707
Ensembl ID		ENSG00000189409	ENSG00000173221
Uniprot IDs		O75900	P35754
PDB IDs			1B4Q 1JHB
Enriched GO Terms of Interacting Partners?		Protein Deglutathionylation Positive Regulation Of Sodium Ion Transmembrane Transporter Activity Positive Regulation Of Sodium Ion Transmembrane Transport Nucleobase-containing Small Molecule Interconversion Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Sodium Ion Transport Positive Regulation Of Membrane Potential Positive Regulation Of Ion Transmembrane Transporter Activity Positive Regulation Of Transporter Activity Regulation Of Sodium Ion Transport Positive Regulation Of Ion Transmembrane Transport Cell Redox Homeostasis Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Positive Regulation Of Ion Transport Regulation Of Membrane Potential Regulation Of Ion Transmembrane Transport	Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Positive Regulation Of Neuron Death Peptidyl-tyrosine Dephosphorylation Involved In Inactivation Of Protein Kinase Activity Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Zymogen Activation Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Glutamate Catabolic Process To 2-oxoglutarate Glutamate Catabolic Process To Aspartate Aspartate Biosynthetic Process Positive Regulation Of Endopeptidase Activity Odontogenesis Positive Regulation Of Peptidase Activity Fumarate Metabolic Process Regulation Of Protein Kinase Activity Aspartate Catabolic Process 4-hydroxyproline Catabolic Process Regulation Of Hepatocyte Growth Factor Receptor Signaling Pathway Regulation Of Kinase Activity Intrinsic Apoptotic Signaling Pathway L-kynurenine Metabolic Process Platelet-derived Growth Factor Receptor-beta Signaling Pathway Carbon Dioxide Transport Cellular Response To Oxidative Stress Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Negative Regulation Of Protein Kinase Activity Glutamate Catabolic Process Pancreatic Juice Secretion Glial Cell Apoptotic Process Negative Regulation Of Kinase Activity Protein Processing Regulation Of Apoptotic DNA Fragmentation Aspartate Metabolic Process Saliva Secretion Regulation Of Protein Phosphorylation Regulation Of Neuron Death Positive Regulation Of Proteolysis Negative Regulation Of Transferase Activity Glycerol Transport Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of Protein Phosphorylation Negative Regulation Of Activated T Cell Proliferation Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C Kynurenine Metabolic Process Dicarboxylic Acid Catabolic Process Polyol Transport Cellular Water Homeostasis Apoptotic Signaling Pathway
Tagcloud ?		antisense biochemically defective degrades ecm genetically gfp green gut hepatocyte maintaining mammals messenger metalloproteinase mmps morphants morpholino ortholog pancreas pathophysiology physiology reductions rescued tnfa tnfb versa vice warrant zebrafish	affymetrix agtr1 benjamini cdkn1c crh cytotrophoblast dscr1 gatm gnas hochberg hpgd imprinted indo inhba intrauterine iugr lep maternally meg3 mest paternally phlda2 placentae plagl1 psg slc solute u133a villous
Tagcloud (Difference) ?		antisense biochemically defective degrades ecm genetically gfp green gut hepatocyte maintaining mammals messenger metalloproteinase mmps morphants morpholino ortholog pancreas pathophysiology physiology reductions rescued tnfa tnfb versa vice warrant zebrafish	affymetrix agtr1 benjamini cdkn1c crh cytotrophoblast dscr1 gatm gnas hochberg hpgd imprinted indo inhba intrauterine iugr lep maternally meg3 mest paternally phlda2 placentae plagl1 psg slc solute u133a villous
Tagcloud (Intersection) ?