GLRX and MMP23B

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		GLRX	MMP23B
Gene Name		glutaredoxin (thioltransferase)	matrix metallopeptidase 23B
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion Cytosol Extracellular Vesicular Exosome	Proteinaceous Extracellular Matrix Intracellular Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Electron Carrier Activity Glutathione Disulfide Oxidoreductase Activity Protein N-terminus Binding Glutathione Oxidoreductase Activity	Metalloendopeptidase Activity Metallopeptidase Activity Zinc Ion Binding
	Biological Process	Nucleobase-containing Small Molecule Interconversion Small Molecule Metabolic Process Cell Redox Homeostasis Positive Regulation Of Membrane Potential Nucleobase-containing Small Molecule Metabolic Process Oxidation-reduction Process Protein Deglutathionylation Positive Regulation Of Sodium Ion Transmembrane Transporter Activity	Reproduction Proteolysis
Pathways		Metabolism of nucleotides Synthesis and interconversion of nucleotide di- and triphosphates
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: AQP5 CASP3 GOT2 MAP3K5 MMP23B NFIC PTPN1	1 interactors: GLRX
Entrez ID		2745	8510
HPRD ID		02707	04503
Ensembl ID		ENSG00000173221	ENSG00000189409
Uniprot IDs		P35754	O75900
PDB IDs		1B4Q 1JHB
Enriched GO Terms of Interacting Partners?		Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Positive Regulation Of Neuron Death Peptidyl-tyrosine Dephosphorylation Involved In Inactivation Of Protein Kinase Activity Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Zymogen Activation Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Glutamate Catabolic Process To 2-oxoglutarate Glutamate Catabolic Process To Aspartate Aspartate Biosynthetic Process Positive Regulation Of Endopeptidase Activity Odontogenesis Positive Regulation Of Peptidase Activity Fumarate Metabolic Process Regulation Of Protein Kinase Activity Aspartate Catabolic Process 4-hydroxyproline Catabolic Process Regulation Of Hepatocyte Growth Factor Receptor Signaling Pathway Regulation Of Kinase Activity Intrinsic Apoptotic Signaling Pathway L-kynurenine Metabolic Process Platelet-derived Growth Factor Receptor-beta Signaling Pathway Carbon Dioxide Transport Cellular Response To Oxidative Stress Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Negative Regulation Of Protein Kinase Activity Glutamate Catabolic Process Pancreatic Juice Secretion Glial Cell Apoptotic Process Negative Regulation Of Kinase Activity Protein Processing Regulation Of Apoptotic DNA Fragmentation Aspartate Metabolic Process Saliva Secretion Regulation Of Protein Phosphorylation Regulation Of Neuron Death Positive Regulation Of Proteolysis Negative Regulation Of Transferase Activity Glycerol Transport Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of Protein Phosphorylation Negative Regulation Of Activated T Cell Proliferation Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C Kynurenine Metabolic Process Dicarboxylic Acid Catabolic Process Polyol Transport Cellular Water Homeostasis Apoptotic Signaling Pathway	Protein Deglutathionylation Positive Regulation Of Sodium Ion Transmembrane Transporter Activity Positive Regulation Of Sodium Ion Transmembrane Transport Nucleobase-containing Small Molecule Interconversion Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Sodium Ion Transport Positive Regulation Of Membrane Potential Positive Regulation Of Ion Transmembrane Transporter Activity Positive Regulation Of Transporter Activity Regulation Of Sodium Ion Transport Positive Regulation Of Ion Transmembrane Transport Cell Redox Homeostasis Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Positive Regulation Of Ion Transport Regulation Of Membrane Potential Regulation Of Ion Transmembrane Transport
Tagcloud ?		affymetrix agtr1 benjamini cdkn1c crh cytotrophoblast dscr1 gatm gnas hochberg hpgd imprinted indo inhba intrauterine iugr lep maternally meg3 mest paternally phlda2 placentae plagl1 psg slc solute u133a villous	antisense biochemically defective degrades ecm genetically gfp green gut hepatocyte maintaining mammals messenger metalloproteinase mmps morphants morpholino ortholog pancreas pathophysiology physiology reductions rescued tnfa tnfb versa vice warrant zebrafish
Tagcloud (Difference) ?		affymetrix agtr1 benjamini cdkn1c crh cytotrophoblast dscr1 gatm gnas hochberg hpgd imprinted indo inhba intrauterine iugr lep maternally meg3 mest paternally phlda2 placentae plagl1 psg slc solute u133a villous	antisense biochemically defective degrades ecm genetically gfp green gut hepatocyte maintaining mammals messenger metalloproteinase mmps morphants morpholino ortholog pancreas pathophysiology physiology reductions rescued tnfa tnfb versa vice warrant zebrafish
Tagcloud (Intersection) ?