GLRX and AQP5

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		GLRX	AQP5
Gene Name		glutaredoxin (thioltransferase)	aquaporin 5
Image
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion Cytosol Extracellular Vesicular Exosome	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Microvillus Basal Plasma Membrane Apical Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Electron Carrier Activity Glutathione Disulfide Oxidoreductase Activity Protein N-terminus Binding Glutathione Oxidoreductase Activity	Protein Binding Water Channel Activity Glycerol Channel Activity
	Biological Process	Nucleobase-containing Small Molecule Interconversion Small Molecule Metabolic Process Cell Redox Homeostasis Positive Regulation Of Membrane Potential Nucleobase-containing Small Molecule Metabolic Process Oxidation-reduction Process Protein Deglutathionylation Positive Regulation Of Sodium Ion Transmembrane Transporter Activity	Water Transport Excretion Cellular Water Homeostasis Carbon Dioxide Transport Glycerol Transport Pancreatic Juice Secretion Ion Transmembrane Transport Odontogenesis Saliva Secretion Camera-type Eye Morphogenesis Transmembrane Transport
Pathways		Metabolism of nucleotides Synthesis and interconversion of nucleotide di- and triphosphates	Passive transport by Aquaporins Aquaporin-mediated transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: AQP5 CASP3 GOT2 MAP3K5 MMP23B NFIC PTPN1	7 interactors: GLRX HNRNPK KRT31 KRT40 MDFI NOTCH2NL WNT2
Entrez ID		2745	362
HPRD ID		02707	02706
Ensembl ID		ENSG00000173221
Uniprot IDs		P35754	P55064
PDB IDs		1B4Q 1JHB	3D9S
Enriched GO Terms of Interacting Partners?		Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Positive Regulation Of Neuron Death Peptidyl-tyrosine Dephosphorylation Involved In Inactivation Of Protein Kinase Activity Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Zymogen Activation Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Glutamate Catabolic Process To 2-oxoglutarate Glutamate Catabolic Process To Aspartate Aspartate Biosynthetic Process Positive Regulation Of Endopeptidase Activity Odontogenesis Positive Regulation Of Peptidase Activity Fumarate Metabolic Process Regulation Of Protein Kinase Activity Aspartate Catabolic Process 4-hydroxyproline Catabolic Process Regulation Of Hepatocyte Growth Factor Receptor Signaling Pathway Regulation Of Kinase Activity Intrinsic Apoptotic Signaling Pathway L-kynurenine Metabolic Process Platelet-derived Growth Factor Receptor-beta Signaling Pathway Carbon Dioxide Transport Cellular Response To Oxidative Stress Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Negative Regulation Of Protein Kinase Activity Glutamate Catabolic Process Pancreatic Juice Secretion Glial Cell Apoptotic Process Negative Regulation Of Kinase Activity Protein Processing Regulation Of Apoptotic DNA Fragmentation Aspartate Metabolic Process Saliva Secretion Regulation Of Protein Phosphorylation Regulation Of Neuron Death Positive Regulation Of Proteolysis Negative Regulation Of Transferase Activity Glycerol Transport Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of Protein Phosphorylation Negative Regulation Of Activated T Cell Proliferation Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C Kynurenine Metabolic Process Dicarboxylic Acid Catabolic Process Polyol Transport Cellular Water Homeostasis Apoptotic Signaling Pathway	Protein Deglutathionylation Embryonic Placenta Development Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Placenta Development Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Iris Morphogenesis Atrial Cardiac Muscle Tissue Morphogenesis Lung Induction Regulation Of Wnt Signaling Pathway Regulation Of Low-density Lipoprotein Particle Clearance Positive Regulation Of Receptor Biosynthetic Process
Tagcloud ?		affymetrix agtr1 benjamini cdkn1c crh cytotrophoblast dscr1 gatm gnas hochberg hpgd imprinted indo inhba intrauterine iugr lep maternally meg3 mest paternally phlda2 placentae plagl1 psg slc solute u133a villous	accordingly aquaporin basis categorize curative ebc epidermal immunohistochemistry intensity marker mcf microarray multivariate overexpressed percentage pr progesterone prognostic prominent score scored staining stating strong sum surgery unfavorable univariate weak
Tagcloud (Difference) ?		affymetrix agtr1 benjamini cdkn1c crh cytotrophoblast dscr1 gatm gnas hochberg hpgd imprinted indo inhba intrauterine iugr lep maternally meg3 mest paternally phlda2 placentae plagl1 psg slc solute u133a villous	accordingly aquaporin basis categorize curative ebc epidermal immunohistochemistry intensity marker mcf microarray multivariate overexpressed percentage pr progesterone prognostic prominent score scored staining stating strong sum surgery unfavorable univariate weak
Tagcloud (Intersection) ?