MIR128-1 and ZFR

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIR128-1	ZFR
Description		microRNA 128-1	zinc finger RNA binding protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space RISC Complex	Nucleus Chromosome Cytoplasm
	Molecular Function	MRNA 3'-UTR Binding MRNA Base-pairing Post-transcriptional Repressor Activity	Nucleic Acid Binding DNA Binding RNA Binding Double-stranded RNA Binding Single-stranded RNA Binding Protein Binding Zinc Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Gene Expression Negative Regulation Of Lipoprotein Particle Clearance Negative Regulation Of Cell Migration MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation MiRNA-mediated Gene Silencing By MRNA Destabilization Cholesterol Homeostasis Positive Regulation Of Cell Adhesion Lipid Homeostasis Cellular Response To Lipopolysaccharide Negative Regulation Of Cholesterol Efflux Negative Regulation Of Lipoprotein Transport Negative Regulation Of Macrophage Colony-stimulating Factor Production Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Brown Fat Cell Differentiation Negative Regulation Of Macrophage Migration
Pathways
Drugs
Diseases
GWAS		Body mass index ( 26426971)	Metabolite levels ( 23823483)
Interacting Genes		91 interacting genes: AIMP1 AIMP2 APOBEC3B ATXN2 ATXN2L C1QBP CASC3 CELF1 CPSF6 CRTAP DARS1 DDX1 DDX21 DDX23 DDX3X DHX36 DHX37 EIF2AK2 EPRS1 FAM98A FUS G3BP2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC LSM10 LSM11 MARS1 MATR3 MSI2 NOL6 NONO NUDT16L1 NUFIP2 PDCD11 PGAM5 PRMT1 PTBP1 PTBP3 PUF60 PURA PURB QARS1 RARS1 RBFOX2 RBM10 RBM12B RBM14 RBM17 RBM4 RTCA RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 SYNCRIP TAF15 TENT2 TRA2A TRA2B U2SURP UPF1 USP36 UTP20 YBX1 YBX2 YBX3 ZFR	46 interacting genes: CEBPA HMGB2 MIR1-1 MIR106A MIR106B MIR128-1 MIR128-2 MIR138-2 MIR145 MIR155 MIR15B MIR16-1 MIR16-2 MIR18A MIR18B MIR19A MIR19B2 MIR200C MIR206 MIR20B MIR21 MIR214 MIR222 MIR29B1 MIR29B2 MIR29C MIR31 MIR34B MIR363 MIR9-1 MIR9-2 MIR9-3 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I RNF10 USP7
Entrez ID		406915	51663
HPRD ID			15730
Ensembl ID		ENSG00000207654	ENSG00000056097
Uniprot IDs			Q05D65 Q96KR1
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process Nucleic Acid Metabolic Process RNA Splicing MRNA Processing MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Binding Macromolecule Metabolic Process Regulation Of RNA Splicing Regulation Of MRNA Metabolic Process Ribonucleoprotein Complex MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Post-transcriptional Regulation Of Gene Expression Nucleus Aminoacyl-tRNA Synthetase Multienzyme Complex Cytoplasmic Stress Granule Nucleoplasm Spliceosomal Complex Regulation Of Translation Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Metabolic Process Catalytic Step 2 Spliceosome Negative Regulation Of RNA Catabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Translation Regulation Of Primary Metabolic Process MRNA 3'-UTR Binding Regulation Of Macromolecule Metabolic Process MiRNA Binding Negative Regulation Of MRNA Catabolic Process RNA Stabilization MRNA Stabilization Negative Regulation Of Metabolic Process Regulation Of Metabolic Process Regulation Of RNA Stability Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Gene Expression RNA Transport TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Regulation Of MRNA Stability TRNA Aminoacylation Nucleolus Negative Regulation Of Gene Expression	RISC Complex MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process MRNA 3'-UTR Binding Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation MRNA Destabilization RNA Destabilization Positive Regulation Of MRNA Catabolic Process Positive Regulation Of MRNA Metabolic Process Extracellular Vesicle Regulation Of MRNA Stability Regulation Of RNA Stability Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Translation Regulation Of Macromolecule Metabolic Process Regulation Of MRNA Metabolic Process Negative Regulation Of Cytokine Production Regulation Of Metabolic Process Positive Regulation Of Catabolic Process Negative Regulation Of Cell Migration Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Angiogenesis Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Extracellular Space Regulation Of Vasculature Development Regulation Of Translation Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Signal Transduction Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Negative Regulation Of Cell Communication Negative Regulation Of Signaling Negative Regulation Of Protein Metabolic Process Regulation Of Cytokine Production Negative Regulation Of Developmental Process
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