SLC61A1 and RNF144A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC61A1	RNF144A
Description		solute carrier family 61 member 1	ring finger protein 144A
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Ubiquitin Ligase Complex Cytoplasm Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Endosome Membrane Membrane Cytoplasmic Vesicle Membrane Organelle Membrane Cytoplasmic Vesicle
	Molecular Function	Protein Binding Molybdate Ion Transmembrane Transporter Activity	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Ubiquitin Conjugating Enzyme Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Monoatomic Ion Transport Molybdate Ion Transport Response To Food Response To Starvation	Pattern Recognition Receptor Signaling Pathway Cytoplasmic Pattern Recognition Receptor Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Protein K6-linked Ubiquitination
Pathways			E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS			Allergic rhinitis ( 30013184) Asthma ( 34103634) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433) Asthma-chronic obstructive pulmonary disease overlap syndrome ( 30657218) Cerebral amyloid angiopathy x APOEe4 status interaction in Alzheimer’s disease ( 34020725) Esophageal adenocarcinoma x smoking interaction ( 29551738) Intracranial aneurysm ( 30823506) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Manic episodes in bipolar disorder ( 26297903) Response to antipsychotic treatment ( 20195266)
Interacting Genes		58 interacting genes: ADGRE2 AQP6 ARL6IP1 BEST2 BLCAP BTNL9 C2CD2L CBARP CCL4L2 CD40 CD79A CLDN7 CLRN1 CREB3 CREB3L1 ERRFI1 FFAR2 FXYD3 GJA5 GLP1R GOSR2 GPR101 GPR152 GPR25 GPR42 GPX8 HSD17B13 IGFBP5 IL27RA KASH5 LAT LHFPL5 LMNA MMGT1 MUC1 PEX19 PKMYT1 PLN RNF144A RNF19B RTP2 SCN3B SHISAL1 SLC10A6 SLC18A2 SLC39A9 SSMEM1 STATH TBXA2R TIMMDC1 TMEM128 TMEM130 TMEM14B TMEM179B TMEM203 TMEM237 XRN1 YIPF6	30 interacting genes: BIRC6 CYSLTR2 DGAT2L6 E2F1 E2F2 E2F3 E2F4 EGFR HSPA2 PAQR6 PARP1 RFT1 SEC22A SGTA SGTB SLC61A1 SLC7A1 TMEM31 UBC UBE2D1 UBE2D2 UBE2H UBE2K UBE2L3 UBE2L6 UBE2V1 UBE2V2 USP21 USP32 YIF1A
Entrez ID		84975	9781
HPRD ID		14416	11510
Ensembl ID		ENSG00000182544	ENSG00000151692
Uniprot IDs		Q6N075	P50876
PDB IDs			1WIM 6L99
Enriched GO Terms of Interacting Partners?		Membrane Plasma Membrane G Protein-coupled Receptor Activity Protein Binding Monoatomic Ion Transport SA Node Cell Action Potential Regulation Of Muscle System Process Endoplasmic Reticulum Membrane Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization G Protein-coupled Receptor Signaling Pathway Regulation Of Atrial Cardiac Muscle Cell Membrane Depolarization Negative Regulation Of Muscle Hypertrophy Localization Within Membrane Response To Testosterone	Ubiquitin Conjugating Enzyme Activity Post-translational Protein Modification Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Ubiquitin-protein Transferase Activity Protein Modification Process Proteolysis TRC Complex Error-free Postreplication DNA Repair Positive Regulation Of Protein Polyubiquitination UBC13-MMS2 Complex DNA-binding Transcription Activator Activity Lens Fiber Cell Apoptotic Process Proteolysis Involved In Protein Catabolic Process Regulation Of Protein Polyubiquitination Ubiquitin Conjugating Enzyme Complex Negative Regulation Of Fat Cell Proliferation Rb-E2F Complex Protein Metabolic Process Protein K48-linked Ubiquitination Positive Regulation Of Protein Ubiquitination Positive Regulation Of Protein Modification Process Modification-dependent Protein Catabolic Process Transcription Regulator Complex RNA Polymerase II Transcription Regulator Complex Positive Regulation Of Post-translational Protein Modification Positive Regulation Of Protein K63-linked Ubiquitination Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Ubiquitin Protein Ligase Binding Macromolecule Metabolic Process Protein Dimerization Activity Regulation Of Protein K63-linked Ubiquitination Protein-containing Complex Macromolecule Catabolic Process Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Ubiquitination Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of Protein Metabolic Process Transferase Activity Ubiquitin-like Protein Transferase Activity Regulation Of DNA Repair Protein Binding Regulation Of Protein Modification Process Regulation Of Post-translational Protein Modification Protein Targeting To ER Positive Regulation Of Macromolecule Metabolic Process NAD+-histone H3S10 Serine ADP-ribosyltransferase Activity Positive Regulation Of RNA Biosynthetic Process NAD+-histone H2BS6 Serine ADP-ribosyltransferase Activity
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