AJUBA and AURKAIP1

Number of citations of the paper that reports this interaction (PMID 13678582)
144

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		AJUBA	AURKAIP1
Gene Name		ajuba LIM protein	aurora kinase A interacting protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasmic MRNA Processing Body Nucleus Transcription Factor Complex Microtubule Organizing Center Cytosol Plasma Membrane Cell-cell Junction Focal Adhesion Lamellipodium	Nucleus Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Chromatin Binding Transcription Corepressor Activity Protein Binding Zinc Ion Binding Alpha-catenin Binding Actin Filament Binding	Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription From RNA Polymerase II Promoter Mitotic Cell Cycle Response To Hypoxia Transcription, DNA-templated Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Lamellipodium Assembly Regulation Of Cell Migration Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Protein Complex Assembly Negative Regulation Of Kinase Activity Cellular Protein Localization Gene Silencing By MiRNA Wound Healing, Spreading Of Epidermal Cells Negative Regulation Of Hippo Signaling Regulation Of GTPase Activity Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of MAP Kinase Activity Glycerophospholipid Biosynthetic Process Focal Adhesion Assembly Regulation Of Cellular Response To Hypoxia Positive Regulation Of Gene Silencing By MiRNA	Organelle Organization Mitochondrial Translation Negative Regulation Of Mitotic Nuclear Division Positive Regulation Of Proteolysis Mitochondrial Translational Initiation Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways		G2/M Transition Mitotic G2-G2/M phases Regulation of PLK1 Activity at G2/M Transition Cell Cycle, Mitotic	Mitochondrial translation Organelle biogenesis and maintenance Mitochondrial translation elongation Mitochondrial translation initiation Mitochondrial translation termination
Drugs
Diseases
GWAS		Primary tooth development (number of teeth) ( 23704328) Primary tooth development (time to first tooth eruption) ( 23704328)
Protein-Protein Interactions		10 interactors: ACTA1 AURKAIP1 AURKB BCAR1 CTNNA1 GFI1B GRB2 LATS2 LCK SLC1A2	3 interactors: AJUBA AURKA FAM9B
Entrez ID		84962	54998
HPRD ID		16426	16457
Ensembl ID		ENSG00000129474	ENSG00000175756
Uniprot IDs		Q96IF1	Q9NWT8
PDB IDs
Enriched GO Terms of Interacting Partners?		Aging Response To Hormone Response To Wounding Response To Organonitrogen Compound Response To Organic Substance Cellular Response To Organonitrogen Compound Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Response To Abiotic Stimulus Organ Development Organelle Organization Platelet Activation Cellular Response To Hormone Stimulus Multicellular Organismal Development Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway B Cell Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Actin Filament Organization Developmental Process Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Enzyme Linked Receptor Protein Signaling Pathway System Development Regulation Of Organelle Organization Immune Response-regulating Cell Surface Receptor Signaling Pathway T Cell Costimulation Response To External Stimulus Negative Regulation Of Cell Division Cellular Response To Organic Substance Blood Coagulation Cell Division Regulation Of Cellular Component Organization Hemostasis Response To Radiation Negative Regulation Of Cell Cycle Response To Peptide Hormone Cytoskeleton Organization Vascular Endothelial Growth Factor Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Skeletal Muscle Fiber Adaptation Negative Regulation Of Integrin-mediated Signaling Pathway Cellular Response To Stimulus Response To Peptide T Cell Receptor Signaling Pathway Anatomical Structure Development Protein Heterooligomerization Histone H3-S28 Phosphorylation D-aspartate Import	G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Spindle Checkpoint Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Spindle Assembly Involved In Female Meiosis I Spindle Assembly Involved In Meiosis Positive Regulation Of Gene Silencing By MiRNA Spindle Stabilization Posttranscriptional Regulation Of Gene Expression Regulation Of Cellular Response To Hypoxia Negative Regulation Of Hippo Signaling Positive Regulation Of Oocyte Maturation Meiotic Spindle Organization Regulation Of Hippo Signaling Protein Localization To Centrosome Mitotic Centrosome Separation Regulation Of Gene Silencing By MiRNA Female Meiosis I Mitotic Cell Cycle Process Positive Regulation Of Oocyte Development Wound Healing, Spreading Of Epidermal Cells Centrosome Separation Mitotic Cell Cycle Protein Localization To Cytoskeleton Histone-serine Phosphorylation Regulation Of Spindle Checkpoint Regulation Of Gene Silencing Cell Cycle Process Positive Regulation Of Cellular Protein Metabolic Process Centrosome Localization Cell Projection Organization Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Focal Adhesion Assembly Positive Regulation Of Protein Metabolic Process Regulation Of Cell Cycle Checkpoint Female Meiotic Division Gene Silencing By MiRNA Negative Regulation Of Microtubule Depolymerization Wound Healing, Spreading Of Cells Histone Phosphorylation Mitotic Spindle Organization Cell Cycle Cellular Protein Localization Posttranscriptional Gene Silencing Positive Regulation Of Mitotic Nuclear Division Adherens Junction Assembly Lamellipodium Assembly Regulation Of Centrosome Cycle Negative Regulation Of Microtubule Polymerization Or Depolymerization Lamellipodium Organization
Tagcloud ?		belongs carp cdna connect contained cytoplasm cytoskeleton entire extracellular frame gcrv grass hybrid immediately immunoprecipitation inducible ip jx01 lim location matrix ns26 orf overlap polypeptide reading responding sub
Tagcloud (Difference) ?		belongs carp cdna connect contained cytoplasm cytoskeleton entire extracellular frame gcrv grass hybrid immediately immunoprecipitation inducible ip jx01 lim location matrix ns26 orf overlap polypeptide reading responding sub
Tagcloud (Intersection) ?