HSH2D and CNMD

Number of citations of the paper that reports this interaction (PubMedID 25814554)
62

Data Source:
BioGRID (two hybrid)

		HSH2D	CNMD
Description		hematopoietic SH2 domain containing	chondromodulin
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Cytosol	Extracellular Region Endomembrane System Membrane
	Molecular Function	Protein Binding Protein-macromolecule Adaptor Activity	Protein Binding
	Biological Process	Negative Regulation Of B Cell Apoptotic Process Signal Transduction T Cell Activation Negative Regulation Of Mitochondrial Depolarization	Skeletal System Development Negative Regulation Of Endothelial Cell Proliferation Proteoglycan Metabolic Process Negative Regulation Of Angiogenesis Cell Differentiation Cartilage Development
Pathways
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		21 interacting genes: AR CNMD CRK EGFR ERBB2 ERBB3 ERBB4 FES GAB1 KIT LDHAL6B MET MPP3 OLIG1 PIK3R3 PINK1 PLPP6 RBP7 TNK2 TSC1 TSG101	6 interacting genes: APPL2 C3orf52 FURIN HLA-DPA1 HSH2D SOCS4
Entrez ID		84941	11061
HPRD ID		12219	05511
Ensembl ID		ENSG00000196684	ENSG00000136110
Uniprot IDs		Q96JZ2	O75829
PDB IDs		2CS0
Enriched GO Terms of Interacting Partners?		Protein Tyrosine Kinase Activity Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme-linked Receptor Protein Signaling Pathway Protein Kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Basal Plasma Membrane ERBB2 Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Kinase Activity Regulation Of Peptidyl-tyrosine Phosphorylation ERBB Signaling Pathway Receptor Complex Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Intracellular Signal Transduction Negative Regulation Of Programmed Cell Death Cellular Developmental Process Regulation Of MAPK Cascade Positive Regulation Of MAPK Cascade Ubiquitin Protein Ligase Binding Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Cell Motility ERBB3:ERBB2 Complex Positive Regulation Of Phosphate Metabolic Process Animal Organ Development Regulation Of Locomotion Positive Regulation Of Cell Migration Positive Regulation Of Epithelial Cell Proliferation Regulation Of Phosphorus Metabolic Process Regulation Of Epithelial Cell Proliferation Regulation Of Anatomical Structure Morphogenesis Positive Regulation Of Locomotion Positive Regulation Of Cell Motility Positive Regulation Of Protein Modification Process Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Epidermal Growth Factor Receptor Activity Neuregulin Receptor Activity Phosphorylation Regulation Of Protein Phosphorylation Cell Surface Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Positive Regulation Of Signal Transduction Regulation Of Protein Modification Process Positive Regulation Of Protein Phosphorylation Regulation Of Cell Population Proliferation Regulation Of Phosphorylation Regulation Of Cell Migration Positive Regulation Of Phosphorylation ErbB-3 Class Receptor Binding ERBB2-ERBB4 Signaling Pathway Cell Population Proliferation	Endosome Membrane Negative Regulation Of Nerve Growth Factor Production Golgi Apparatus Subcompartment Regulation Of Nerve Growth Factor Production Negative Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Dibasic Protein Processing Zymogen Inhibition Transforming Growth Factor Beta Receptor Signaling Pathway Nerve Growth Factor Production Negative Regulation Of Neurotrophin Production Positive Regulation Of Macropinocytosis Positive Regulation Of Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Negative Regulation Of Receptor Catabolic Process Early Phagosome Membrane Cold Acclimation Regulation Of Cytokine Production Endosome Positive Regulation Of Proteolysis Viral Translation Viral Life Cycle Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Cytokine Precursor Processing Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Negative Regulation Of Transforming Growth Factor Beta1 Production Nerve Growth Factor Binding Macropinosome Positive Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Positive Regulation Of Protein Catabolic Process Positive Regulation Of Pinocytosis Regulation Of Immune Response MHC Class II Receptor Activity Signal Peptide Processing Heparan Sulfate Binding Adiponectin-activated Signaling Pathway Negative Regulation Of Mitochondrial Depolarization Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Diet Induced Thermogenesis Peptide Antigen Assembly With MHC Class II Protein Complex Positive Regulation Of Viral Entry Into Host Cell Negative Regulation Of Transforming Growth Factor Beta Production Early Phagosome Cellular Response To Hepatocyte Growth Factor Stimulus Negative Regulation Of Fatty Acid Oxidation Negative Regulation Of D-glucose Import Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Positive Regulation Of Phagocytosis, Engulfment Negative Regulation Of B Cell Apoptotic Process Negative Regulation Of Signaling Receptor Activity Negative Regulation Of Protein Tyrosine Kinase Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?