CORO6 and BLOC1S6

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		CORO6	BLOC1S6
Description		coronin 6	biogenesis of lysosomal organelles complex 1 subunit 6
Image			No pdb structure
GO Annotations	Cellular Component	Lamellipodium	Stress Fiber Ruffle Cytoplasm Endosome Cytosol Focal Adhesion Membrane Transport Vesicle BLOC-1 Complex Cytoplasmic Vesicle Filamentous Actin Cell-cell Contact Zone Contractile Ring Presynapse Axon Cytoplasm Microvesicle
	Molecular Function	Protein Binding Actin Filament Binding	Protein Binding Syntaxin Binding Identical Protein Binding Protein Homodimerization Activity Actin Filament Binding Molecular Adaptor Activity
	Biological Process	Actin Filament Organization Cell Migration Negative Regulation Of Cellular Component Organization	Kidney Development Bradykinin Biosynthetic Process Respiratory System Process Endothelium Development Amino Acid Metabolic Process Glutamate Metabolic Process Glutamine Metabolic Process Protein Targeting Lipid Metabolic Process Phospholipid Metabolic Process Blood Coagulation Memory Anterograde Axonal Transport Protein Secretion Response To Xenobiotic Stimulus Gene Expression Response To Activity Synaptic Vesicle Docking Dentate Gyrus Development Hypothalamus Development Melanocyte Differentiation Lung Development Neuron Projection Development Melanosome Transport Melanosome Organization Positive Regulation Of Natural Killer Cell Activation Secretion Of Lysosomal Enzymes Intracellular Nitric Oxide Homeostasis Multicellular Organism Growth Endosome To Melanosome Transport Vasodilation Circadian Sleep/wake Cycle Pigmentation ATP Metabolic Process Adenosine Metabolic Process Intracellular Transport Lung Alveolus Development Anterograde Synaptic Vesicle Transport Homeostasis Of Number Of Cells Positive Regulation Of Pigment Cell Differentiation Actin Filament Bundle Assembly Lipid Homeostasis Cilium Assembly Membrane Fusion Cellular Response To Epidermal Growth Factor Stimulus Protein Transmembrane Transport Response To Acetylcholine
Pathways			Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Coronary artery disease ( 29212778) Heel bone mineral density ( 30598549)
Interacting Genes		3 interacting genes: BLOC1S6 CRK FXR1	49 interacting genes: ABI2 AGGF1 ANK1 APP BLOC1S1 BLOC1S2 BLOC1S4 C4orf46 CCDC136 CCDC22 CCHCR1 CCR2 CDK5R1 CEP44 CORO6 DCTN2 DTNBP1 EPS8 EXOC8 HAUS1 IFT20 INSYN1 KRT13 KRT72 LURAP1 MED21 MLPH NDC80 NDN NTAQ1 NUP62 OLFM2 PLEKHA5 PLEKHF2 RABGEF1 RINT1 SKA1 SLC4A1 SMN1 SMN2 SNAPIN STX11 STX12 STX1A SYCE3 TPM1 TPM3 TRAK1 WASHC3
Entrez ID		84940	26258
HPRD ID		08607	16055
Ensembl ID		ENSG00000167549	ENSG00000104164
Uniprot IDs		B3KRY9 B3KSZ9 Q6QEF8	B3KY40 H3BST1 Q9UL45
PDB IDs		7KYX
Enriched GO Terms of Interacting Partners?		Dentate Gyrus Development Organelle Assembly Positive Regulation Of Small GTPase Mediated Signal Transduction Bradykinin Biosynthetic Process Circadian Sleep/wake Cycle Cellular Response To Growth Factor Stimulus Helper T Cell Diapedesis Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Cellular Localization Regulation Of Small GTPase Mediated Signal Transduction Diapedesis Cerebellar Neuron Development Response To Growth Factor Protein Phosphorylated Amino Acid Binding Positive Regulation Of Receptor Clustering Negative Regulation Of Defense Response Cellular Response To Insulin-like Growth Factor Stimulus Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Reelin-mediated Signaling Pathway Response To Endothelin Cellular Response To Endothelin Response To Cholecystokinin Postsynaptic Specialization Assembly Presynapse RNA Strand Annealing Activity Positive Regulation Of Long-term Neuronal Synaptic Plasticity Negative Regulation Of Long-term Synaptic Potentiation Nuclear Pore Localization Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Positive Regulation Of MiRNA-mediated Gene Silencing Intracellular Membraneless Organelle Nuclear Pore Complex Assembly Positive Regulation Of Developmental Pigmentation Synaptic Vesicle Docking Secretion Of Lysosomal Enzymes Adenosine Metabolic Process Intracellular Nitric Oxide Homeostasis Endosome To Melanosome Transport Positive Regulation Of Pigment Cell Differentiation Response To Acetylcholine Microvesicle Contractile Ring Response To Hepatocyte Growth Factor Neuron Projection Development Cellular Response To Nitric Oxide Localization Within Membrane Regulation Of Receptor Clustering Insulin-like Growth Factor Receptor Binding Cellular Response To Reactive Nitrogen Species Cellular Component Assembly	Organelle Localization BLOC-1 Complex Establishment Of Localization In Cell Intracellular Transport Cellular Localization Axo-dendritic Transport Organelle Organization Establishment Of Organelle Localization Microtubule-based Process Establishment Of Vesicle Localization Anterograde Synaptic Vesicle Transport Vesicle Organization Transport Along Microtubule Vesicle Localization Vesicle Transport Along Microtubule Cytoskeleton-dependent Intracellular Transport Microtubule-based Transport Vesicle Cytoskeletal Trafficking Axon Cytoplasm Axonal Transport Protein Transport Establishment Of Protein Localization Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Vesicle-mediated Transport Anterograde Axonal Transport Organelle Transport Along Microtubule Intracellular Protein Localization Cytoplasm Cytosol Neuron Projection Neuron Projection Development Regulation Of Lysosome Size BORC Complex Microtubule-based Movement Exocytosis Growth Cone Cytoskeleton Organization Perikaryon Regulation Of Endosome Size Cytoplasmic Side Of Lysosomal Membrane Cell Projection Organization Supramolecular Fiber Organization Regulation Of Supramolecular Fiber Organization Centrosome Secretion By Cell Regulation Of Vesicle Size Lysosome Localization PTB Domain Binding
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?