ADGRG7 and LDLRAD1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		ADGRG7	LDLRAD1
Description		adhesion G protein-coupled receptor G7	low density lipoprotein receptor class A domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity Protein Binding	Protein Binding
	Biological Process	Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway	Vesicle-mediated Transport
Pathways
Drugs
Diseases
GWAS			Parkinson disease and lewy body pathology ( 25663231)
Interacting Genes		4 interacting genes: LDLRAD1 LMNA SORT1 VAPA	34 interacting genes: ADGRG7 ANKRD46 AQP1 BNIP2 BNIP3 BNIP3L CMTM7 CTXN3 CXCL9 EBP EMP3 GIMAP5 GPR25 IGFBP5 LAPTM5 MAL MALL MARCHF2 NINJ2 OLFM4 PLN PLPP6 PTTG1IP SEC22A SLC1A1 SLC41A2 TMEM147 TMEM190 TMEM218 TMEM79 UNC93B1 VAMP4 VTI1B ZFPL1
Entrez ID		84873	388633
HPRD ID		17060	17372
Ensembl ID		ENSG00000144820	ENSG00000203985
Uniprot IDs		B7Z303 E9PHI0 Q6ZMH4 Q96K78	Q5T700
PDB IDs
Enriched GO Terms of Interacting Partners?		Nuclear Membrane Protein Localization To Organelle Perinuclear Region Of Cytoplasm Neurotensin Receptor Activity, Non-G Protein-coupled DNA Double-strand Break Attachment To Nuclear Envelope Structural Constituent Of Nuclear Lamina Nerve Growth Factor Receptor Activity Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Lamin Filament Cellular Localization Ventricular Cardiac Muscle Cell Development Nuclear Pore Localization Establishment Of Protein Localization To Organelle Negative Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Negative Regulation Of Mesenchymal Cell Proliferation Intracellular Transport Vesicle Organization Golgi To Lysosome Transport Plasma Membrane To Endosome Transport Vesicle-mediated Transport Retromer Complex Binding Golgi Vesicle Transport Nerve Growth Factor Binding Cerebellar Climbing Fiber To Purkinje Cell Synapse Endoplasmic Reticulum Localization FFAT Motif Binding Host-mediated Activation Of Viral Genome Replication COPII-coated Vesicle Budding Sphingomyelin Biosynthetic Process Endoplasmic Reticulum-plasma Membrane Tethering Host-mediated Perturbation Of Viral Genome Replication Establishment Of Localization In Cell Protein Folding In Endoplasmic Reticulum Nuclear Lamina Host-mediated Suppression Of Viral Genome Replication Protein Localization To Nuclear Envelope Golgi To Endosome Transport Nerve Growth Factor Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Organelle Localization Negative Regulation Of Release Of Cytochrome C From Mitochondria Intracellular Protein Localization Golgi To Vacuole Transport Trans-Golgi Network Transport Vesicle D-glucose Import Protein Localization To Endoplasmic Reticulum Ceramide Transport Sphingomyelin Metabolic Process Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Nuclear Envelope Organization	Membrane Presynaptic Endosome Membrane Cellular Response To Mercury Ion Positive Regulation Of Membrane Permeability Lysosome Nuclear Envelope Response To Mercury Ion Mitochondrial Protein Catabolic Process Endoplasmic Reticulum Membrane Mitochondrial Outer Membrane Permeabilization Structural Constituent Of Myelin Sheath Response To Oxygen-glucose Deprivation Neurotransmitter Receptor Transport To Plasma Membrane Defense Response To Virus Negative Regulation Of Mitochondrial Membrane Potential Protein Binding Negative Regulation Of Membrane Potential Response To Decreased Oxygen Levels Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Mitochondrial Envelope Regulation Of Membrane Permeability Neurotransmitter Receptor Transport Response To Oxygen Levels Endoplasmic Reticulum Mitochondrial Outer Membrane Permeabilization Involved In Programmed Cell Death Establishment Of Protein Localization Golgi To Vacuole Transport Establishment Of Protein Localization To Membrane Lysosomal Membrane Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Defense Response Nitric Oxide Transmembrane Transporter Activity Negative Regulation Of Programmed Cell Death Metanephric Proximal Convoluted Tubule Segment 2 Development Nuclear Membrane Membrane Organization Response To Virus Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Positive Regulation Of Mitochondrial Membrane Permeability Mitochondrion Autophagosome Adaptor Activity Hair Follicle Morphogenesis Negative Regulation Of Skeletal Muscle Hypertrophy Protein Insertion Into Plasma Membrane Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane Circadian Sleep/wake Cycle, Sleep Phospholamban Complex Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Involved In Heart Process Vesicle-mediated Transport D-aspartate Transmembrane Transporter Activity
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