ERMN and RTN4IP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ERMN	RTN4IP1
Description		ermin	reticulon 4 interacting protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Cell Cortex Filopodium Internode Region Of Axon Paranode Region Of Axon Neuronal Cell Body Myelin Sheath Extracellular Exosome Glial Cell Projection	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Matrix Membrane
	Molecular Function	Actin Binding Protein Binding Actin Filament Binding	Nucleotide Binding Protein Binding Zinc Ion Binding NADPH Dehydrogenase (quinone) Activity Oxidoreductase Activity
	Biological Process	Morphogenesis Of A Branching Structure Actin Filament Organization Regulation Of Cell Shape Regulation Of Cell Projection Organization	Ubiquinone Biosynthetic Process Nervous System Development Regulation Of Dendrite Development
Pathways
Drugs
Diseases
GWAS			Daytime sleep phenotypes ( 27126917) Metabolite levels ( 23823483)
Interacting Genes		3 interacting genes: APP NEDD4 RTN4IP1	23 interacting genes: ARFGAP3 CALCOCO2 CBFA2T3 CENPK CTAG1A CTAG1B ERMN EXOC7 GGA2 HDX MARCHF5 PPP1R8 PYM1 RELA RTN4 RTN4R RUNX1T1 SCAF1 SMURF2 SORBS1 WBP11 WWTR1 ZYX
Entrez ID		57471	84816
HPRD ID		13838	18008
Ensembl ID		ENSG00000136541	ENSG00000130347
Uniprot IDs		B4DIZ1 Q8TAM6	Q8WWV3
PDB IDs			2VN8
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex Regulation Of Plasma Membrane Bounded Cell Projection Organization PTB Domain Binding Regulation Of Spontaneous Synaptic Transmission Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway System Development Regulation Of Synapse Organization Response To Light Stimulus Intermediate-density Lipoprotein Particle Regulation Of Cell Projection Organization Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition NMDA Selective Glutamate Receptor Signaling Pathway Amylin Binding Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Protein Catabolic Process Regulation Of Synapse Structure Or Activity Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Toll Signaling Pathway Regulation Of Monoatomic Ion Transmembrane Transport Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Regulation Of Monoatomic Cation Transmembrane Transport Synapse Organization Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Channel Inhibitor Activity Phosphoserine Residue Binding Nuclear Receptor-mediated Corticosteroid Signaling Pathway Beta-2 Adrenergic Receptor Binding Phosphothreonine Residue Binding Regulation Of Dendrite Development Negative Regulation Of Potassium Ion Export Across Plasma Membrane	RNA Metabolic Process
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