NFKBID and IRX6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NFKBID	IRX6
Description		NFKB inhibitor delta	iroquois homeobox 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromatin Nucleus
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding
	Biological Process	Inflammatory Response Regulation Of Gene Expression T Cell Receptor Signaling Pathway Positive Regulation Of T-helper 17 Cell Differentiation	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Neuron Differentiation Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Cell Development
Pathways
Drugs
Diseases
GWAS			Hypospadias ( 25108383) Lack of premeditation ( 30718321) Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355) Visceral fat ( 22589738)
Interacting Genes		111 interacting genes: ADAMTSL4 AIRIM ANXA11 ARHGEF2 BEX2 C1orf94 CCHCR1 CRYBA2 CTRC CYB5R2 DDX25 DMRT3 DTX3 EFHC2 ELOA ESR2 FAAP20 FAM107A FARS2 FOXI1 GADD45GIP1 GFAP GIGYF1 GLYCTK GPANK1 GRB10 HDAC4 HNRNPF HNRNPH1 HOXA1 HOXB5 HOXC8 HOXC9 HOXD3 HSBP1L1 IHO1 IKZF3 INCA1 IRX6 KICS2 KRT19 KRT34 KRT40 KRT75 KRT76 KRTAP6-2 LCK LGALS14 LHX3 LMO2 LMO3 LMO4 MEOX2 MRPL28 MRPL53 MYEF2 NCK2 NDUFB7 NICN1 NUP54 PATL1 PATZ1 PAX6 PKP1 PLEKHN1 POMC POU4F2 PRDM6 PRMT7 PSMB8 PTCD1 QARS1 RAD51D RBM14 RBM41 RBM4B RFX2 RING1 RSPH1 RTP5 RUNX1 SAMD11 SAMD4A SCNM1 SH2D1B SH3RF1 SLU7 SMAD4 SMG9 SNAPC3 SORBS3 SPMIP2 SS18 SSC4D TCF19 TCF4 TCL1A TEKT4 TEKT5 TFIP11 TRAF2 TRIM29 TRIM9 TRIML2 TSEN54 TSSK3 UTP23 VIM ZBTB16 ZC2HC1B ZIC1	11 interacting genes: ARID5A CRX GLRX3 HOXA1 KRTAP19-7 MEOX2 NFKBID PFDN5 TBX19 TLE5 TRIB3
Entrez ID		84807	79190
HPRD ID		18140	12091
Ensembl ID		ENSG00000167604	ENSG00000159387
Uniprot IDs		A0A286YF31 A0AAQ5BIF9 Q8NI38	P78412
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of Transcription By RNA Polymerase II Intermediate Filament Organization Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Nucleus RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of RNA Metabolic Process Intermediate Filament Regulation Of Transcription By RNA Polymerase II Cell Differentiation DNA-binding Transcription Factor Activity Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Structural Constituent Of Skin Epidermis Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of RNA Biosynthetic Process Positive Regulation Of RNA Metabolic Process Cellular Developmental Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Anterior/posterior Pattern Specification Chromatin Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nuclear Speck Neuron Fate Specification Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Metabolic Process Pattern Specification Process Regionalization RNA Metabolic Process Sequence-specific Double-stranded DNA Binding Positive Regulation Of Biosynthetic Process Developmental Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cell Fate Specification Positive Regulation Of Macromolecule Metabolic Process Ventral Spinal Cord Interneuron Specification MRNA Splicing, Via Spliceosome Supramolecular Fiber Organization Keratin Filament CD27 Signaling Pathway Embryonic Morphogenesis RNA Splicing, Via Transesterification Reactions Axonemal A Tubule Inner Sheath RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding	Transcription Corepressor Activity Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of T-helper 17 Type Immune Response Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Transcription By RNA Polymerase II Regulation Of T-helper 17 Type Immune Response Regulation Of Macromolecule Biosynthetic Process Nucleus Sequence-specific Double-stranded DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Activity Positive Regulation Of Transcription By RNA Polymerase II Semicircular Canal Formation RNA Polymerase III Assembly RNA Polymerase I Assembly Regulation Of Macromolecule Metabolic Process Retina Development In Camera-type Eye Abducens Nerve Formation Optokinetic Behavior RNA Polymerase II Core Complex Assembly Regulation Of Metabolic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Primary Metabolic Process Sequence-specific DNA Binding Somite Specification Positive Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Positive Regulation Of Adaptive Immune Response Ubiquitin-protein Transferase Regulator Activity Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of RNA Metabolic Process Chromatin DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of 3'-UTR-mediated MRNA Stabilization
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