IRX6

Description		iroquois homeobox 6
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Neuron Differentiation Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Cell Development
Pathways
Drugs
Diseases
GWAS		Hypospadias ( 25108383) Lack of premeditation ( 30718321) Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355) Visceral fat ( 22589738)
Interacting Genes		11 interacting genes: ARID5A CRX GLRX3 HOXA1 KRTAP19-7 MEOX2 NFKBID PFDN5 TBX19 TLE5 TRIB3
Entrez ID		79190
HPRD ID		12091
Ensembl ID		ENSG00000159387
Uniprot IDs		P78412
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription Corepressor Activity Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of T-helper 17 Type Immune Response Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Transcription By RNA Polymerase II Regulation Of T-helper 17 Type Immune Response Regulation Of Macromolecule Biosynthetic Process Nucleus Sequence-specific Double-stranded DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Activity Positive Regulation Of Transcription By RNA Polymerase II Semicircular Canal Formation RNA Polymerase III Assembly RNA Polymerase I Assembly Regulation Of Macromolecule Metabolic Process Retina Development In Camera-type Eye Abducens Nerve Formation Optokinetic Behavior RNA Polymerase II Core Complex Assembly Regulation Of Metabolic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Primary Metabolic Process Sequence-specific DNA Binding Somite Specification Positive Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Positive Regulation Of Adaptive Immune Response Ubiquitin-protein Transferase Regulator Activity Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of RNA Metabolic Process Chromatin DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of 3'-UTR-mediated MRNA Stabilization
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