SMARCA5 and SATB1

Number of citations of the paper that reports this interaction (PMID 12374985)
99

Data Source:
HPRD (in vitro)

		SMARCA5	SATB1
Gene Name		SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	SATB homeobox 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Condensed Chromosome Nucleus Nucleoplasm Chromatin Silencing Complex Nucleolus NURF Complex RSF Complex Nuclear Replication Fork	Nucleus Nucleoplasm Nuclear Heterochromatin Nuclear Matrix PML Body
	Molecular Function	DNA Binding Helicase Activity Protein Binding ATP Binding ATPase Activity Nucleosome Binding Histone Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Chromatin Binding Double-stranded DNA Binding Protein Binding
	Biological Process	Chromatin Silencing At RDNA Double-strand Break Repair Nucleosome Assembly Chromatin Remodeling DNA-templated Transcription, Initiation Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Nucleosome Positioning CENP-A Containing Nucleosome Assembly Regulation Of Gene Expression, Epigenetic ATP-dependent Chromatin Remodeling Negative Regulation Of Gene Expression, Epigenetic	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Chromatin Remodeling Transcription, DNA-templated Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Epidermis Development Viral Process Histone Methylation CD4-positive, Alpha-beta T Cell Differentiation CD8-positive, Alpha-beta T Cell Differentiation Activated T Cell Proliferation Reflex
Pathways		NoRC negatively regulates rRNA expression Chromosome Maintenance Nucleosome assembly Deposition of new CENPA-containing nucleosomes at the centromere Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression	Apoptotic cleavage of cellular proteins Programmed Cell Death Apoptotic execution phase
Drugs
Diseases
GWAS			Platelet counts ( 22139419)
Protein-Protein Interactions		17 interactors: BAZ1A BAZ1B BAZ2A CDT1 CHRAC1 CREB1 CTNNB1 DNMT3B H3F3A HDAC2 HIST1H3A HIST4H4 MAF POLE3 RAD21 RSF1 SATB1	23 interactors: BAZ1A CASP6 CBX4 CHD3 CUX1 DYT10 EP300 GATA3 HDAC1 KAT2B MTA2 PIAS1 PIAS3 PIAS4 POLR2J SIRT1 SMARCA5 SUMO1 SUMO1P1 SUMO3 TOPORS UBE2I UBR5
Entrez ID		8467	6304
HPRD ID		04538	03647
Ensembl ID		ENSG00000153147	ENSG00000182568
Uniprot IDs		O60264	Q01826
PDB IDs			1YSE 2L1P 2O49 2O4A 3NZL 3TUO
Enriched GO Terms of Interacting Partners?		Chromatin Organization Chromatin Silencing Chromosome Organization Chromatin Remodeling Nucleobase-containing Compound Metabolic Process Chromatin Modification Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Organelle Organization Negative Regulation Of Gene Expression, Epigenetic DNA Metabolic Process Negative Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Gene Silencing Regulation Of Gene Expression, Epigenetic DNA Methylation On Cytosine Negative Regulation Of Gene Expression Chromatin Silencing At RDNA Negative Regulation Of Biosynthetic Process DNA Methylation Regulation Of Transcription, DNA-templated Chromatin Assembly Or Disassembly Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process DNA Modification Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Gene Expression Chromatin Assembly DNA Packaging Histone Modification Methylation Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Cellular Metabolic Process DNA Conformation Change Fungiform Papilla Formation Nucleosome Assembly DNA Replication-independent Nucleosome Assembly Regulation Of Metabolic Process Nucleosome Organization Fungiform Papilla Morphogenesis Protein-DNA Complex Assembly Transcription, DNA-templated Fungiform Papilla Development	Protein Sumoylation Peptidyl-lysine Modification Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Protein Modification By Small Protein Conjugation RNA Biosynthetic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Peptidyl-amino Acid Modification Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Chromatin Modification Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process RNA Metabolic Process Nitrogen Compound Metabolic Process Chromatin Organization Positive Regulation Of Metabolic Process Gene Expression Chromatin Remodeling Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Cellular Protein Modification Process Chromosome Organization Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Sumoylation Positive Regulation Of Cellular Biosynthetic Process Cellular Metabolic Process Regulation Of Protein Metabolic Process Biosynthetic Process Regulation Of Protein Sumoylation Positive Regulation Of Transcription, DNA-templated Regulation Of Androgen Receptor Signaling Pathway Cellular Protein Metabolic Process
Tagcloud ?		baz2a bc bladder characterizing fgfr3 formulation lowered messenger micrornas mir mirna mtor oncogenes oncogenesis oncomir ploidy promoted promoting qrt representative respective rnas rt4 supposed t24 thap2 today transfection urothelial	biomarker clinicopathologic confidence depth endometrial federation gynecology hazards histological international interval invasion lymphatic metastasis myometrial node obstetrics organizer overexpressed parameter predicting prognostic rich serve serves special treating untreated worse
Tagcloud (Difference) ?		baz2a bc bladder characterizing fgfr3 formulation lowered messenger micrornas mir mirna mtor oncogenes oncogenesis oncomir ploidy promoted promoting qrt representative respective rnas rt4 supposed t24 thap2 today transfection urothelial	biomarker clinicopathologic confidence depth endometrial federation gynecology hazards histological international interval invasion lymphatic metastasis myometrial node obstetrics organizer overexpressed parameter predicting prognostic rich serve serves special treating untreated worse
Tagcloud (Intersection) ?