SMARCA5 and RSF1

Number of citations of the paper that reports this interaction (PMID 12972596)
22

Data Source:
HPRD (in vivo)

		SMARCA5	RSF1
Gene Name		SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	remodeling and spacing factor 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Condensed Chromosome Nucleus Nucleoplasm Chromatin Silencing Complex Nucleolus NURF Complex RSF Complex Nuclear Replication Fork	Nucleus Nucleoplasm RSF Complex
	Molecular Function	DNA Binding Helicase Activity Protein Binding ATP Binding ATPase Activity Nucleosome Binding Histone Binding	Protein Binding Zinc Ion Binding ATPase Activity Histone Binding
	Biological Process	Chromatin Silencing At RDNA Double-strand Break Repair Nucleosome Assembly Chromatin Remodeling DNA-templated Transcription, Initiation Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Nucleosome Positioning CENP-A Containing Nucleosome Assembly Regulation Of Gene Expression, Epigenetic ATP-dependent Chromatin Remodeling Negative Regulation Of Gene Expression, Epigenetic	Nucleosome Assembly Chromatin Remodeling DNA-templated Transcription, Initiation Nucleosome Positioning CENP-A Containing Nucleosome Assembly Negative Regulation Of DNA Binding Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Viral Transcription
Pathways		NoRC negatively regulates rRNA expression Chromosome Maintenance Nucleosome assembly Deposition of new CENPA-containing nucleosomes at the centromere Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression	Chromosome Maintenance Nucleosome assembly Deposition of new CENPA-containing nucleosomes at the centromere
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: BAZ1A BAZ1B BAZ2A CDT1 CHRAC1 CREB1 CTNNB1 DNMT3B H3F3A HDAC2 HIST1H3A HIST4H4 MAF POLE3 RAD21 RSF1 SATB1	3 interactors: CSNK2A1 NFKB1 SMARCA5
Entrez ID		8467	51773
HPRD ID		04538	10537
Ensembl ID		ENSG00000153147	ENSG00000048649
Uniprot IDs		O60264	Q05DG0 Q96T23
PDB IDs
Enriched GO Terms of Interacting Partners?		Chromatin Organization Chromatin Silencing Chromosome Organization Chromatin Remodeling Nucleobase-containing Compound Metabolic Process Chromatin Modification Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Organelle Organization Negative Regulation Of Gene Expression, Epigenetic DNA Metabolic Process Negative Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Gene Silencing Regulation Of Gene Expression, Epigenetic DNA Methylation On Cytosine Negative Regulation Of Gene Expression Chromatin Silencing At RDNA Negative Regulation Of Biosynthetic Process DNA Methylation Regulation Of Transcription, DNA-templated Chromatin Assembly Or Disassembly Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process DNA Modification Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Gene Expression Chromatin Assembly DNA Packaging Histone Modification Methylation Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Cellular Metabolic Process DNA Conformation Change Fungiform Papilla Formation Nucleosome Assembly DNA Replication-independent Nucleosome Assembly Regulation Of Metabolic Process Nucleosome Organization Fungiform Papilla Morphogenesis Protein-DNA Complex Assembly Transcription, DNA-templated Fungiform Papilla Development	Negative Regulation Of Interleukin-12 Biosynthetic Process Positive Regulation Of Wnt Signaling Pathway Negative Regulation Of Calcidiol 1-monooxygenase Activity Positive Regulation Of Hyaluronan Biosynthetic Process Regulation Of Wnt Signaling Pathway Negative Regulation Of Vitamin D Biosynthetic Process Positive Regulation Of MiRNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Nucleosome Positioning Transcription, DNA-templated Cellular Response To Nicotine RNA Biosynthetic Process Regulation Of Calcidiol 1-monooxygenase Activity Negative Regulation Of Cholesterol Transport Regulation Of MiRNA Metabolic Process Negative Regulation Of Monooxygenase Activity Regulation Of Vitamin Metabolic Process Regulation Of Interleukin-12 Biosynthetic Process Chromatin Silencing At RDNA Membrane Protein Intracellular Domain Proteolysis Negative Regulation Of Interleukin-12 Production RNA Metabolic Process Response To Copper Ion Negative Regulation Of Steroid Biosynthetic Process Negative Regulation Of Lipid Transport Negative Regulation Of Steroid Metabolic Process Negative Regulation Of Oxidoreductase Activity Gene Expression Cellular Response To Interleukin-6 Negative Regulation Of Catalytic Activity CENP-A Containing Nucleosome Assembly Negative Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Macrophage Derived Foam Cell Differentiation Macromolecule Biosynthetic Process Response To Interleukin-6 Negative Regulation Of Protein Metabolic Process Positive Regulation Of Lipid Storage Histone Exchange Chromatin Silencing DNA Replication-independent Nucleosome Assembly Membrane Protein Proteolysis Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Cytokine Biosynthetic Process Regulation Of Cholesterol Transport Apoptotic Process Response To Nicotine Mitotic Spindle Checkpoint Cellular Response To Alkaloid
Tagcloud ?		baz2a bc bladder characterizing fgfr3 formulation lowered messenger micrornas mir mirna mtor oncogenes oncogenesis oncomir ploidy promoted promoting qrt representative respective rnas rt4 supposed t24 thap2 today transfection urothelial	11q adjusting adjuvant amplification amplified benefit besides biomarkers ccnd1 clinico copy estrogen estrogens ma measure node obtain os pathologic placebo predictive preferentially premenopausal rfs select spacing tamoxifen unlike yrs
Tagcloud (Difference) ?		baz2a bc bladder characterizing fgfr3 formulation lowered messenger micrornas mir mirna mtor oncogenes oncogenesis oncomir ploidy promoted promoting qrt representative respective rnas rt4 supposed t24 thap2 today transfection urothelial	11q adjusting adjuvant amplification amplified benefit besides biomarkers ccnd1 clinico copy estrogen estrogens ma measure node obtain os pathologic placebo predictive preferentially premenopausal rfs select spacing tamoxifen unlike yrs
Tagcloud (Intersection) ?