SMARCA5 and CHRAC1

Number of citations of the paper that reports this interaction (PMID 12434153)
68

Data Source:
HPRD (in vivo)

		SMARCA5	CHRAC1
Gene Name		SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	chromatin accessibility complex 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Condensed Chromosome Nucleus Nucleoplasm Chromatin Silencing Complex Nucleolus NURF Complex RSF Complex Nuclear Replication Fork	Epsilon DNA Polymerase Complex CHRAC
	Molecular Function	DNA Binding Helicase Activity Protein Binding ATP Binding ATPase Activity Nucleosome Binding Histone Binding	DNA Binding DNA-directed DNA Polymerase Activity Sequence-specific DNA Binding Protein Heterodimerization Activity
	Biological Process	Chromatin Silencing At RDNA Double-strand Break Repair Nucleosome Assembly Chromatin Remodeling DNA-templated Transcription, Initiation Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Nucleosome Positioning CENP-A Containing Nucleosome Assembly Regulation Of Gene Expression, Epigenetic ATP-dependent Chromatin Remodeling Negative Regulation Of Gene Expression, Epigenetic	Chromatin Remodeling DNA Biosynthetic Process
Pathways		NoRC negatively regulates rRNA expression Chromosome Maintenance Nucleosome assembly Deposition of new CENPA-containing nucleosomes at the centromere Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: BAZ1A BAZ1B BAZ2A CDT1 CHRAC1 CREB1 CTNNB1 DNMT3B H3F3A HDAC2 HIST1H3A HIST4H4 MAF POLE3 RAD21 RSF1 SATB1	5 interactors: APP BAZ1A FAM9B POLE3 SMARCA5
Entrez ID		8467	54108
HPRD ID		04538	06275
Ensembl ID		ENSG00000153147	ENSG00000104472
Uniprot IDs		O60264	Q9NRG0
PDB IDs
Enriched GO Terms of Interacting Partners?		Chromatin Organization Chromatin Silencing Chromosome Organization Chromatin Remodeling Nucleobase-containing Compound Metabolic Process Chromatin Modification Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Organelle Organization Negative Regulation Of Gene Expression, Epigenetic DNA Metabolic Process Negative Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Gene Silencing Regulation Of Gene Expression, Epigenetic DNA Methylation On Cytosine Negative Regulation Of Gene Expression Chromatin Silencing At RDNA Negative Regulation Of Biosynthetic Process DNA Methylation Regulation Of Transcription, DNA-templated Chromatin Assembly Or Disassembly Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process DNA Modification Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Gene Expression Chromatin Assembly DNA Packaging Histone Modification Methylation Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Cellular Metabolic Process DNA Conformation Change Fungiform Papilla Formation Nucleosome Assembly DNA Replication-independent Nucleosome Assembly Regulation Of Metabolic Process Nucleosome Organization Fungiform Papilla Morphogenesis Protein-DNA Complex Assembly Transcription, DNA-templated Fungiform Papilla Development	Chromatin Modification Chromatin Organization Chromosome Organization Synaptic Growth At Neuromuscular Junction DNA Metabolic Process Chromatin Remodeling Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition DNA Replication Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Nucleosome Positioning Axon Choice Point Recognition Nucleobase-containing Compound Metabolic Process Neuron Remodeling Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Chromatin Silencing At RDNA Nitrogen Compound Metabolic Process Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle CENP-A Containing Nucleosome Assembly Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Histone Exchange Chromatin Silencing DNA Replication-independent Nucleosome Assembly Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Histone H3 Acetylation Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Centromere Complex Assembly Organelle Organization Axon Cargo Transport Mating Neuromuscular Junction Development RNA Metabolic Process Positive Regulation Of Mitotic Cell Cycle Phase Transition Neuron Apoptotic Process Positive Regulation Of Cell Cycle Phase Transition
Tagcloud ?		baz2a bc bladder characterizing fgfr3 formulation lowered messenger micrornas mir mirna mtor oncogenes oncogenesis oncomir ploidy promoted promoting qrt representative respective rnas rt4 supposed t24 thap2 today transfection urothelial	17q 17q12 17q23 8q 8q23 8q24 agar amplicon amplicons amplifications amplified anchorage belonging boosted carry clonogenic colonies driver eif3h encode genomics grb7 indeed investigating overexpressed presenting rad21 screens tanc2
Tagcloud (Difference) ?		baz2a bc bladder characterizing fgfr3 formulation lowered messenger micrornas mir mirna mtor oncogenes oncogenesis oncomir ploidy promoted promoting qrt representative respective rnas rt4 supposed t24 thap2 today transfection urothelial	17q 17q12 17q23 8q 8q23 8q24 agar amplicon amplicons amplifications amplified anchorage belonging boosted carry clonogenic colonies driver eif3h encode genomics grb7 indeed investigating overexpressed presenting rad21 screens tanc2
Tagcloud (Intersection) ?