RSF1 and SMARCA5

Number of citations of the paper that reports this interaction (PubMedID 12972596)
29

Data Source:
HPRD (in vivo)

		RSF1	SMARCA5
Description		remodeling and spacing factor 1	SNF2 related chromatin remodeling ATPase 5
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm RSF Complex	Chromatin Condensed Chromosome Fibrillar Center Nucleus Nucleoplasm Chromatin Silencing Complex Chromosome Pericentric Heterochromatin Nucleolus CHRAC NURF Complex ACF Complex ISWI-type Complex RSF Complex Site Of Double-strand Break Nuclear Replication Fork WICH Complex NoRC Complex CERF Complex B-WICH Complex
	Molecular Function	Protein Binding Zinc Ion Binding ATP Hydrolysis Activity Histone Binding Metal Ion Binding Histone Octamer Slider Activity	DNA Binding Chromatin Binding Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity Nucleosome Binding Histone Binding ATP-dependent Chromatin Remodeler Activity Nucleosome Array Spacer Activity Histone Octamer Slider Activity
	Biological Process	Chromatin Organization Nucleosome Assembly Chromatin Remodeling DNA-templated Transcription Initiation Regulation Of DNA-templated Transcription Negative Regulation Of DNA Binding Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Viral Transcription	RDNA Heterochromatin Formation Regulation Of DNA Replication DNA Repair Chromatin Organization Nucleosome Assembly Chromatin Remodeling DNA Methylation-dependent Constitutive Heterochromatin Formation DNA-templated Transcription Initiation Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II DNA Damage Response Negative Regulation Of Transcription By RNA Polymerase I Heterochromatin Formation Positive Regulation Of DNA Replication Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase I Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase III Antiviral Innate Immune Response Negative Regulation Of Mitotic Chromosome Condensation Cellular Response To Leukemia Inhibitory Factor
Pathways		Deposition of new CENPA-containing nucleosomes at the centromere	NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Deposition of new CENPA-containing nucleosomes at the centromere
Drugs			Beta-D-Glucose 4-Deoxy-Alpha-D-Glucose
Diseases
GWAS		Left-handedness ( 32989287) Tourette syndrome ( 30818990)	Appendicular lean mass ( 33097823) Height ( 31562340) Malaria ( 31844061)
Interacting Genes		6 interacting genes: CDK1 CSNK2A1 HMGB1 NFKB1 PLK1 SMARCA5	20 interacting genes: BAZ1A BAZ1B BAZ2A CDT1 CHRAC1 CREB1 CTNNB1 DNMT3B GSK3A H3-3A H3C1 H4C16 HDAC2 MAF POLE3 PTEN RAD21 RSF1 SATB1 USP7
Entrez ID		51773	8467
HPRD ID		10537	04538
Ensembl ID		ENSG00000048649	ENSG00000153147
Uniprot IDs		Q05DG0 Q96T23	O60264
PDB IDs			6NE3 8V4Y 8V6V 8V7L 9E1L 9E1M 9E1N 9E1O 9E1P 9E1Q 9E1R 9E1U 9E1V 9E1W 9E1X
Enriched GO Terms of Interacting Partners?		Protein Localization To Site Of Double-strand Break Regulation Of DNA Metabolic Process DNA Repair Double-strand Break Repair Via Nonhomologous End Joining Negative Regulation Of Cell Cycle Process Mitotic Nuclear Membrane Disassembly DNA Metabolic Process Protein Localization To Chromosome DNA Damage Response Negative Regulation Of Cell Cycle DNA Damage Checkpoint Signaling Nuclear Membrane Disassembly Membrane Disassembly Regulation Of Chromosome Segregation Signal Transduction In Response To DNA Damage Negative Regulation Of Gene Expression Nucleic Acid Metabolic Process Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Mitotic G2 DNA Damage Checkpoint Signaling Negative Regulation Of Cell Cycle Phase Transition Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Double-strand Break Repair Condensed Chromosome Chromosome Condensation Regulation Of DNA Repair DNA Recombination Spindle Microtubule Regulation Of Chromosome Organization Positive Regulation Of DNA Replication Negative Regulation Of Double-strand Break Repair Negative Regulation Of DNA Repair Regulation Of Apoptotic Process Nucleobase-containing Compound Metabolic Process Nuclear Membrane Organization Regulation Of Transcription By RNA Polymerase II Centrosome Cycle Positive Regulation Of DNA Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Macromolecule Biosynthetic Process Regulation Of Programmed Cell Death Regulation Of Cell Cycle Process G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of DNA Recombination Mitotic G2/M Transition Checkpoint Cellular Response To Stress Cell Cycle G2/M Phase Transition Negative Regulation Of Metabolic Process Pronuclear Fusion	Chromatin Remodeling Chromatin Organization Protein-DNA Complex Assembly Nucleosome Assembly Nucleosome Organization Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Nucleus Regulation Of Macromolecule Metabolic Process CHRAC Negative Regulation Of Metabolic Process Epigenetic Regulation Of Gene Expression Regulation Of Metabolic Process Pericentric Heterochromatin DNA Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Nucleoplasm Negative Regulation Of Biosynthetic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Chromatin Negative Regulation Of Gene Expression, Epigenetic Macromolecule Metabolic Process Cellular Component Assembly Regulation Of Transcription By RNA Polymerase II Nucleic Acid Metabolic Process Fungiform Papilla Formation Protein-containing Complex Assembly Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Chromosome Organization Negative Regulation Of Chromosome Condensation Regulation Of DNA Replication Negative Regulation Of RNA Metabolic Process Protein-containing Complex Organization Hair Follicle Placode Formation Epsilon DNA Polymerase Complex Regulation Of DNA Metabolic Process Positive Regulation Of Metabolic Process Heterochromatin Formation Negative Regulation Of Gene Expression DNA Replication DNA-templated DNA Replication Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleobase-containing Compound Metabolic Process
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