SPZ1 and HOXB9

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		SPZ1	HOXB9
Gene Name		spermatogenic leucine zipper 1	homeobox B9
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleoplasm Mitochondrion
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity	Protein Binding Sequence-specific DNA Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Transcription, DNA-templated Anterior/posterior Pattern Specification Mammary Gland Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Embryonic Skeletal System Development Canonical Wnt Signaling Pathway Cell Chemotaxis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: APP DTNB HOXB9 KDM1A	23 interactors: BTG1 BTG2 CALCOCO2 CREBBP EP300 GOLGA2 HOPX ING4 KRTAP10-9 KRTAP4-12 KRTAP5-9 MDFI MID2 MYBBP1A PHTF1 PNMA1 RBPMS SAT1 SOX15 SPZ1 TAL1 TRIP6 ZNF408
Entrez ID		84654	3219
HPRD ID		15440	00852
Ensembl ID		ENSG00000164299	ENSG00000170689
Uniprot IDs		Q9BXG8	B3KPJ1 P17482
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Protein Binding Regulation Of Primitive Erythrocyte Differentiation Positive Regulation Of Transcription, DNA-templated Synaptic Growth At Neuromuscular Junction Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Collateral Sprouting In Absence Of Injury Regulation Of Binding Regulation Of Transcription From RNA Polymerase II Promoter Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation Blood Coagulation Hemostasis Forebrain Development Neuron Remodeling Positive Regulation Of Megakaryocyte Differentiation Gland Development Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Hormone Biosynthetic Process Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Body Fluid Levels Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Wound Healing Chemotaxis Granulocyte Differentiation Organ Development Cellular Copper Ion Homeostasis Regulation Of Megakaryocyte Differentiation Negative Regulation Of Histone Methylation RNA Metabolic Process Response To Wounding Positive Regulation Of Erythrocyte Differentiation Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Copper Ion Homeostasis Suckling Behavior Regulation Of Histone H3-K4 Methylation Negative Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Metabolic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Brain Development	Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Gene Expression Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process RNA Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Transcription, DNA-templated N-terminal Peptidyl-lysine Acetylation Nucleobase-containing Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription RNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Gene Expression Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Skeletal Muscle Tissue Regeneration Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter N-terminal Protein Amino Acid Acetylation Regulation Of Binding Histone Acetylation Signal Transduction By P53 Class Mediator Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia N-terminal Protein Amino Acid Modification Response To Stress Regulation Of Protein Binding Chromatin Organization Regulation Of Cellular Response To Heat Histone Modification Regulation Of Protein Import Into Nucleus Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Protein Localization To Nucleus Regulation Of Cellular Process Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Wound Healing
Tagcloud ?			10kb appbp2 arhgap32 bcas3 breakpoints ccdc49 coamplification col14a1 coregulator ddx5 depdc6 deptor enpp2 lasp1 leukaemias nrip1 oprd1 painting pcgf2 phf20l1 plec1 skap1 taok1 tiam1 timm23 trps1 unamplified usp32 zmym4
Tagcloud (Difference) ?			10kb appbp2 arhgap32 bcas3 breakpoints ccdc49 coamplification col14a1 coregulator ddx5 depdc6 deptor enpp2 lasp1 leukaemias nrip1 oprd1 painting pcgf2 phf20l1 plec1 skap1 taok1 tiam1 timm23 trps1 unamplified usp32 zmym4
Tagcloud (Intersection) ?