SRRM4 and ARL6IP4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SRRM4	ARL6IP4
Description		serine/arginine repetitive matrix 4	ARF like GTPase 6 interacting protein 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleolus Nuclear Speck
	Molecular Function	RNA Binding MRNA Binding Protein Binding Identical Protein Binding	RNA Binding Protein Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Nervous System Development Sensory Perception Of Sound RNA Splicing Cell Differentiation Neuron Maturation Regulation Of RNA Splicing	MRNA Processing RNA Splicing
Pathways
Drugs
Diseases
GWAS		Cerebrospinal fluid t-tau levels in normal cognition ( 29274321) Facial morphology (factor 3, length of philtrum) ( 28441456) Loneliness ( 27629369) Loneliness (linear analysis) ( 27629369) Photic sneeze reflex ( 27182965) Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis ( 26980576) Stroke ( 32693751)	Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Schizophrenia ( 23974872 25056061 29483656) Tourette syndrome ( 30818990)
Interacting Genes		34 interacting genes: - AKAP17A ARL6IP4 C16orf87 C1orf35 CACNA1A CDC37 CLK1 CLK4 FAM9B LUC7L LUC7L2 LUZP4 MCRS1 PRPF38A RBM25 RBM39 RBMX2 RNPS1 RSRC1 SNIP1 SNRNP70 SREK1 SRRM1 SRSF11 SRSF4 TBC1D26 U2AF1 WDR5 ZNF124 ZNF286A ZNF699 ZRSR2 ZRSR2P1	21 interacting genes: AP1M1 ARL6 C1orf35 CEBPA CSNK2A1 ETS1 FOS IKBKG KRCC1 NKAPD1 NKAPL RBM39 RNF41 SREK1 SRPK2 SRRM4 SRSF11 THAP1 TRIM55 TRIM63 WEE2-AS1
Entrez ID		84530	51329
HPRD ID		13897	09640
Ensembl ID		ENSG00000139767	ENSG00000182196
Uniprot IDs		A7MD48 V5T9A0	A0A0C4DG62 A0A0C4DH18 A0A8C8KBE9 F8WCT1 F8WEP2 Q66PJ3
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing RNA Splicing, Via Transesterification Reactions Nuclear Speck Spliceosomal Complex RNA Binding MRNA Splicing, Via Spliceosome Regulation Of RNA Splicing RNA Metabolic Process Nucleic Acid Binding Nucleic Acid Metabolic Process Nucleus Regulation Of MRNA Splicing, Via Spliceosome Pre-mRNA 3'-splice Site Binding RS Domain Binding U2AF Complex Regulation Of MRNA Processing Nucleobase-containing Compound Metabolic Process U2-type Prespliceosome U1 SnRNP MRNA Binding Regulation Of MRNA Metabolic Process Protein-RNA Complex Assembly U1 SnRNP Binding Spliceosomal Complex Assembly U2-type Precatalytic Spliceosome NSL Complex Regulation Of Alternative MRNA Splicing, Via Spliceosome Nucleoplasm Precatalytic Spliceosome Negative Regulation Of MRNA Splicing, Via Spliceosome Histone Acetyltransferase Complex U2-type Prespliceosome Assembly Negative Regulation Of RNA Splicing U2 SnRNP Protein Serine/threonine/tyrosine Kinase Activity MLL1 Complex Histone H3Q5ser Reader Activity MRNA Splice Site Recognition Macromolecule Metabolic Process Negative Regulation Of Protein Refolding Histone H3K4me1 Reader Activity HSP90-CDC37 Chaperone Complex	RNA Metabolic Process Identical Protein Binding Nucleic Acid Metabolic Process MRNA Metabolic Process RNA Splicing MRNA Processing Nuclear Body Organization Regulation Of MRNA Splicing, Via Spliceosome
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