HOPX and EPC1

Number of citations of the paper that reports this interaction (PMID 17192267)
9

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		HOPX	EPC1
Gene Name		HOP homeobox	enhancer of polycomb homolog 1 (Drosophila)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Nuclear Membrane Piccolo NuA4 Histone Acetyltransferase Complex NuA4 Histone Acetyltransferase Complex
	Molecular Function	DNA Binding	Histone Acetyltransferase Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Trophectodermal Cell Differentiation Transcription, DNA-templated Heart Development Regulation Of Heart Contraction Histone Deacetylation Regulation Of Protein Binding Positive Regulation Of Skeletal Muscle Tissue Regeneration Negative Regulation Of Cell Differentiation Lung Alveolus Development Positive Regulation Of Striated Muscle Cell Differentiation	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Transcription, DNA-templated Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways			Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS			Sexual dysfunction (female) ( 22509378)
Protein-Protein Interactions		7 interactors: EPC1 HDAC2 HOXB9 SRF TCF12 TLX3 ZSCAN1	5 interactors: E2F6 HOPX KRT15 RINT1 TRIM27
Entrez ID		84525	80314
HPRD ID		06280	09941
Ensembl ID		ENSG00000171476	ENSG00000120616
Uniprot IDs		Q9BPY8	Q68DJ2 Q9H2F5
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Eyelid Development In Camera-type Eye Transcription, DNA-templated Regulation Of Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Neuron Differentiation Positive Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Neurogenesis Positive Regulation Of Cellular Biosynthetic Process RNA Metabolic Process Regulation Of Cell Development Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Cardiac Muscle Cell Development Positive Regulation Of Neurogenesis Hippocampus Development Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Cellular Metabolic Process Contractile Actin Filament Bundle Assembly Positive Regulation Of Cell Development Nucleobase-containing Compound Metabolic Process Muscle Structure Development Limbic System Development Regulation Of Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cardiac Muscle Cell Differentiation Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Growth Generation Of Neurons Regulation Of Cell Differentiation Cardiocyte Differentiation Neurogenesis Regulation Of Muscle Cell Differentiation Striated Muscle Cell Development Maintenance Of Chromatin Silencing Negative Regulation Of Beta-amyloid Clearance Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Muscle Cell Development	Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Interleukin-2 Secretion Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Skeletal Muscle Tissue Regeneration Negative Regulation Of Calcium Ion Import Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Interferon-gamma Secretion Regulation Of DNA Damage Checkpoint Negative Regulation Of Viral Release From Host Cell Regulation Of ER To Golgi Vesicle-mediated Transport Regulation Of Transcription From RNA Polymerase II Promoter Interferon-gamma Production Negative Regulation Of Interleukin-2 Production Negative Regulation Of Viral Transcription Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Regulation Of Viral Release From Host Cell Regulation Of Calcium Ion Import Trophectodermal Cell Differentiation Negative Regulation Of Cellular Metabolic Process
Tagcloud ?		absorptive anhydrase brdu bromodeoxyuridine caii carbonic cga chromogranin crypts enterocytes enteroendocrine epcam gastrin goblet iesc isomaltase mcm2 minichromosome muc2 mucin obstacle ph3 porcine reserve sim somatostatin sox9 sucrase villin	aberrantly aforementioned aurkb bcrp bortezomib ccnb1 cd138 cdc2 cenp centrosome downregulate entity evidences g2 immunomodulatory incurable initiating lenalidomide mdr1 myeloma organs polycomb possess proteasome psma5 sp ube3c upregulated works
Tagcloud (Difference) ?		absorptive anhydrase brdu bromodeoxyuridine caii carbonic cga chromogranin crypts enterocytes enteroendocrine epcam gastrin goblet iesc isomaltase mcm2 minichromosome muc2 mucin obstacle ph3 porcine reserve sim somatostatin sox9 sucrase villin	aberrantly aforementioned aurkb bcrp bortezomib ccnb1 cd138 cdc2 cenp centrosome downregulate entity evidences g2 immunomodulatory incurable initiating lenalidomide mdr1 myeloma organs polycomb possess proteasome psma5 sp ube3c upregulated works
Tagcloud (Intersection) ?