HOPX

Description		HOP homeobox
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Cytoplasm
	Molecular Function	DNA Binding Protein Binding Histone Deacetylase Regulator Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Trophectodermal Cell Differentiation Bundle Of His Development Regulation Of Transcription By RNA Polymerase II Heart Development Regulation Of Heart Contraction Cell Differentiation Positive Regulation Of Skeletal Muscle Tissue Regeneration Negative Regulation Of Cell Differentiation Lung Alveolus Development Chaperone-mediated Protein Complex Assembly Positive Regulation Of Striated Muscle Cell Differentiation Positive Regulation Of Gap Junction Assembly
Pathways		Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
Drugs
Diseases
GWAS		Cadmium levels ( 26025379) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Reticulocyte fraction of red cells ( 32888494) Systemic sclerosis ( 30247649)
Novel Interacting Genes		1 novel interacting genes: COMT
Interacting Genes		10 interacting genes: BUB1B EPC1 HDAC2 HOXB9 PICK1 PTGER4 SRF TCF12 TLX3 ZSCAN1
Entrez ID		84525
HPRD ID		06280
Ensembl ID		ENSG00000171476
Uniprot IDs		Q9BPY8
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Dopamine Chromatin Sequence-specific Double-stranded DNA Binding Response To Oxygen Levels Eyelid Development In Camera-type Eye Long-term Synaptic Depression Response To Catecholamine Animal Organ Development Monoamine Transport Response To Amphetamine DNA-binding Transcription Factor Binding Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Synaptic Transmission Response To Cocaine DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Response To Amine Norepinephrine Secretion Catechol O-methyltransferase Activity Cellular Response To Nutrient Levels Response To Alcohol Response To Hormone Developmental Process Positive Regulation Of Male Mating Behavior Positive Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Factor Activity Negative Regulation Of Eosinophil Extravasation Serum Response Element Binding Cellular Developmental Process Negative Regulation Of Cellular Component Organization Response To Decreased Oxygen Levels Cellular Response To Phosphate Starvation Macromolecule Biosynthetic Process Regulation Of DNA-templated Transcription Negative Regulation Of Cell Motility Negative Regulation Of Cell Migration Protein De-2-hydroxyisobutyrylase Activity Regulation Of RNA Biosynthetic Process Negative Regulation Of Eosinophil Migration Bronchus Cartilage Development Cis-regulatory Region Sequence-specific DNA Binding Lung Smooth Muscle Development Negative Regulation Of Locomotion Response To Alkaloid Mitotic Checkpoint Complex Meiotic Sister Chromatid Cohesion, Centromeric Habituation Mastication Renal Sodium Excretion Renal Albumin Absorption Renin Secretion Into Blood Stream
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