MYO19 and DHX16

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		MYO19	DHX16
Description		myosin XIX	DEAH-box helicase 16
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Cytosol Cytoskeleton Actin Cytoskeleton Membrane Myosin Complex	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm U2-type Precatalytic Spliceosome Ribonucleoprotein Complex
	Molecular Function	Microfilament Motor Activity Nucleotide Binding Cytoskeletal Motor Activity Actin Binding ATP Binding Cytoskeletal Protein Binding ATP Hydrolysis Activity Myosin Light Chain Binding Actin Filament Binding Plus-end Directed Microfilament Motor Activity	Nucleotide Binding Nucleic Acid Binding RNA Binding RNA Helicase Activity Helicase Activity Protein Binding ATP Binding ATP-dependent Activity, Acting On RNA Hydrolase Activity ATP Hydrolysis Activity Pattern Recognition Receptor Activity Ubiquitin Binding Molecular Adaptor Activity
	Biological Process	Endocytosis Actin Filament Organization Regulation Of Cytokinesis Mitochondrion Migration Along Actin Filament Establishment Of Mitochondrion Localization Regulation Of Mitochondrial Fission Mitocytosis	MRNA Splicing, Via Spliceosome Immune System Process MRNA Processing RNA Splicing Innate Immune Response Antiviral Innate Immune Response
Pathways		RHOT2 GTPase cycle RHOT1 GTPase cycle	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Body mass index ( 26426971 28552196 29273807) Chronic kidney disease ( 31152163) Estimated glomerular filtration rate ( 31015462 31152163)	Autism spectrum disorder or schizophrenia ( 28540026) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		1 interacting genes: DHX16	13 interacting genes: APP APPBP2 COIL CSNK2A1 ESS2 HOMEZ MEGF10 MYO19 RIGI RNF10 SNRNP27 TFIP11 XAB2
Entrez ID		80179	8449
HPRD ID		10107	04555
Ensembl ID		ENSG00000278259	ENSG00000204560
Uniprot IDs		B4E218 B7Z1T7 Q96H55	A0A1U9X7L7 B4DZ28 O60231 Q5SQH4 Q5SQH5
PDB IDs			5Z56 5Z57 5Z58 6FF7 7DVQ 7QTT 8CH6 8I0R 8I0S 8I0T 8I0U 8I0V
Enriched GO Terms of Interacting Partners?		Cytotoxic T Cell Pyroptotic Cell Death ATP-dependent Activity, Acting On RNA Defense Response To Other Organism Defense Response To Symbiont Pyroptotic Cell Death Wide Pore Channel Activity Granzyme-mediated Programmed Cell Death Signaling Pathway Cardiolipin Binding Defense Response Pattern Recognition Receptor Activity Response To Other Organism Response To External Biotic Stimulus U2-type Precatalytic Spliceosome Biological Process Involved In Interaction With Symbiont Phosphatidylinositol-4-phosphate Binding Pyroptotic Inflammatory Response Killing By Host Of Symbiont Cells Phosphatidylserine Binding Antiviral Innate Immune Response RNA Helicase Activity Phosphatidylinositol-4,5-bisphosphate Binding Defense Response To Gram-negative Bacterium Ubiquitin Binding Helicase Activity Killing Of Cells Of Another Organism Phospholipid Binding	MRNA Metabolic Process MRNA Splicing, Via Spliceosome Spliceosomal Complex RNA Splicing, Via Transesterification Reactions Catalytic Step 2 Spliceosome RNA Splicing MRNA Processing RNA Metabolic Process Negative Regulation Of DNA Repair Negative Regulation Of Double-strand Break Repair Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Mitochondrion Migration Along Actin Filament
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