DOC2A and RAP1GDS1

Number of citations of the paper that reports this interaction (PMID 24722188)
1

Data Source:
BioGRID (two hybrid)

		DOC2A	RAP1GDS1
Gene Name		double C2-like domains, alpha	RAP1, GTP-GDP dissociation stimulator 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosome Cell Junction Synaptic Vesicle Membrane Neuron Projection	Mitochondrion Endoplasmic Reticulum Cytosol Extracellular Vesicular Exosome
	Molecular Function	Transporter Activity Protein Binding Calcium-dependent Phospholipid Binding	GTPase Activator Activity
	Biological Process	Synaptic Transmission Nervous System Development Synaptic Vesicle Exocytosis Regulation Of Calcium Ion-dependent Exocytosis	Vascular Smooth Muscle Contraction Myosin Filament Assembly Positive Regulation Of Rho GTPase Activity Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Positive Regulation Of Mitochondrial Calcium Ion Concentration
Pathways
Drugs
Diseases
GWAS			Biochemical measures ( 19260141)
Protein-Protein Interactions		5 interactors: DYNLT1 RAP1GDS1 STXBP1 UBASH3B UNC13B	13 interactors: CDC42 DOC2A EGFR HRAS KIFAP3 KRAS MBIP NRAS PLEKHB1 RAC1 RAP1A RHOA ZNF451
Entrez ID		8448	5910
HPRD ID		05195	11763
Ensembl ID		ENSG00000149927	ENSG00000138698
Uniprot IDs		Q14183	B3KNU0 P52306 Q6U7G8
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Synaptic Vesicle Priming Glutamate Secretion Regulation Of Synaptic Vesicle Exocytosis Establishment Of Organelle Localization Regulation Of Synaptic Vesicle Transport Organelle Localization Acid Secretion Positive Regulation Of Exocytosis Vesicle Docking Involved In Exocytosis Regulation Of Neurotransmitter Secretion Vesicle Docking Dicarboxylic Acid Transport Membrane Docking Neurotransmitter Secretion Positive Regulation Of Synaptic Vesicle Priming Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus Synaptic Vesicle Transport Regulation Of Neurotransmitter Levels Positive Regulation Of Synaptic Vesicle Exocytosis Regulation Of Exocytosis Amino Acid Transport Regulation Of Synaptic Plasticity Neurotransmitter Transport Establishment Of Vesicle Localization Regulation Of Cellular Localization Vesicle Localization Regulation Of Synaptic Vesicle Fusion To Presynaptic Membrane Axon Target Recognition Positive Regulation Of Inhibitory Postsynaptic Membrane Potential Intracellular Transport Of Viral Protein In Host Cell Myosin Filament Assembly Regulation Of Signaling Regulation Of Rho GTPase Activity Negative Regulation Of Synaptic Transmission, GABAergic Regulation Of SNARE Complex Assembly Carboxylic Acid Transport Regulation Of Synaptic Transmission Organic Acid Transport Synaptic Vesicle Docking Positive Regulation Of Secretion Synaptic Vesicle Priming Regulation Of Protein Complex Assembly Regulation Of Rho Protein Signal Transduction Exocytosis Cellular Protein Complex Assembly Positive Regulation Of Mitochondrial Calcium Ion Concentration Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Negative Regulation Of Platelet Aggregation Regulation Of Vesicle-mediated Transport Regulation Of Short-term Neuronal Synaptic Plasticity	Neurotrophin TRK Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Neurotrophin Signaling Pathway Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Activation Of MAPKK Activity Wound Healing Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Axon Guidance Response To Wounding Positive Regulation Of Rac Protein Signal Transduction Regulation Of Kinase Activity Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Kinase Activity Fc Receptor Signaling Pathway Axonogenesis Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Transferase Activity Axon Development Cellular Response To Growth Factor Stimulus Cell Morphogenesis Involved In Neuron Differentiation Response To Growth Factor Chemotaxis Small GTPase Mediated Signal Transduction Regulation Of MAPK Cascade Neuron Projection Morphogenesis Regulation Of Protein Phosphorylation Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Positive Regulation Of Ras Protein Signal Transduction Epithelium Development Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Protein Phosphorylation Cell Morphogenesis Involved In Differentiation Regulation Of Intracellular Signal Transduction Regulation Of Protein Kinase Activity Positive Regulation Of DNA Replication Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of MAPK Cascade Positive Regulation Of Signal Transduction Ras Protein Signal Transduction Neuron Projection Development Regulation Of Phosphorylation Immune Response-regulating Signaling Pathway Leukocyte Migration Fc-epsilon Receptor Signaling Pathway Cell Migration Cell Projection Morphogenesis
Tagcloud ?			adapted af4 aml1 b2a2 b3a2 considerations consuming correspondence e1a2 e2a enl evaluable expensive laborious leukemic lymphoblastic mll multicenter multiplex nup98 p190 p210 pallisgaard pbx1 rt sil strengthen tal1 tel
Tagcloud (Difference) ?			adapted af4 aml1 b2a2 b3a2 considerations consuming correspondence e1a2 e2a enl evaluable expensive laborious leukemic lymphoblastic mll multicenter multiplex nup98 p190 p210 pallisgaard pbx1 rt sil strengthen tal1 tel
Tagcloud (Intersection) ?