DUSP11 and SRSF7

Number of citations of the paper that reports this interaction (PMID 9685386)
5

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DUSP11	SRSF7
Gene Name		dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)	serine/arginine-rich splicing factor 7
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nuclear Speck	Nucleus Nucleoplasm Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	RNA Binding Polynucleotide 5'-phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Tyrosine/serine/threonine Phosphatase Activity Phosphatase Activity Poly(A) RNA Binding Nucleotide Phosphatase Activity, Acting On Free Nucleotides	Nucleotide Binding Protein Binding Zinc Ion Binding Poly(A) RNA Binding
	Biological Process	RNA Processing RNA Metabolic Process Peptidyl-tyrosine Dephosphorylation Polynucleotide 5' Dephosphorylation	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Processing MRNA Export From Nucleus RNA Splicing Gene Expression MRNA 3'-end Processing Negative Regulation Of MRNA Splicing, Via Spliceosome
Pathways			mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway Transport of Mature Transcript to Cytoplasm Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing
Drugs
Diseases
GWAS		Creatinine levels ( 20383145) Metabolite levels ( 21931564)
Protein-Protein Interactions		3 interactors: QARS SRSF7 SRSF9	13 interactors: CCNL2 CDK19 CDK6 CPSF6 DUSP11 LUC7L2 NEDD4 NXF1 PCBP2 SDCBP SREK1 SRPK1 SRPK2
Entrez ID		8446	6432
HPRD ID		04368	08991
Ensembl ID		ENSG00000144048	ENSG00000115875
Uniprot IDs		C9JYA6 O75319	C9JAB2 Q16629
PDB IDs			2HVZ
Enriched GO Terms of Interacting Partners?		Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Termination Of RNA Polymerase II Transcription Regulation Of MRNA Splicing, Via Spliceosome MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus MRNA 3'-end Processing Regulation Of MRNA Processing Regulation Of RNA Splicing RNA 3'-end Processing Nuclear Export MRNA Transport RNA Transport RNA Localization Glutaminyl-tRNA Aminoacylation Negative Regulation Of Gene Expression Prolyl-tRNA Aminoacylation MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleocytoplasmic Transport Nuclear Transport Glutamyl-tRNA Aminoacylation RNA Splicing Negative Regulation Of Cellular Metabolic Process MRNA Processing MRNA Metabolic Process RNA Processing Cytoplasmic Transport RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter MRNA Splice Site Selection Nucleobase-containing Compound Metabolic Process Spliceosomal Complex Assembly Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Translation Intracellular Transport Nitrogen Compound Metabolic Process TRNA Aminoacylation For Protein Translation TRNA Aminoacylation Cellular Component Assembly Cellular Response To Interferon-gamma Establishment Of Localization In Cell	RNA Processing MRNA Processing MRNA Metabolic Process RNA Splicing Gene Expression Positive Regulation Of Viral Genome Replication RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Negative Regulation Of Viral Genome Replication Spliceosomal Complex Assembly Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Cell Dedifferentiation Nuclear Speck Organization Transmission Of Virus Development Involved In Symbiotic Interaction Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Negative Regulation Of Viral Process Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Processing Regulation Of Cell Cycle Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of RNA Splicing Polynucleotide 5' Dephosphorylation Cellular Nitrogen Compound Metabolic Process Nucleus Organization Positive Regulation Of Extracellular Vesicular Exosome Assembly Cellular Metabolic Process Viral Process Regulation Of Extracellular Vesicular Exosome Assembly Progesterone Receptor Signaling Pathway Regulation Of Viral Process Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Ribonucleoprotein Complex Assembly Cellular Protein Metabolic Process Immune Response Immune System Process Cellular Protein Modification Process Protein Phosphorylation Glucocorticoid Receptor Signaling Pathway Sperm Chromatin Condensation Poly(A)+ MRNA Export From Nucleus Negative Regulation Of Cellular Senescence Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Protein Targeting To Lysosome
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