DUSP11

Description		dual specificity phosphatase 11
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GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Mitochondrion Nuclear Speck Intercellular Bridge
	Molecular Function	RNA Binding Polynucleotide 5'-phosphatase Activity Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Hydrolase Activity Phosphatase Activity
	Biological Process	RNA Processing Protein Dephosphorylation
Pathways
Drugs
Diseases
GWAS		Creatinine levels ( 20383145) Lean body mass ( 28552196) Metabolite levels ( 21931564) Serum metabolite levels ( 23093944)
Interacting Genes		3 interacting genes: QARS1 SRSF7 SRSF9
Entrez ID		8446
HPRD ID		04368
Ensembl ID		ENSG00000144048
Uniprot IDs		O75319
PDB IDs		4JMJ 4MBB 4NYH
Enriched GO Terms of Interacting Partners?		Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Glutamine-tRNA Ligase Activity Glutaminyl-tRNA Aminoacylation Regulation Of RNA Splicing Negative Regulation Of RNA Metabolic Process RNA Metabolic Process Protein Domain Specific Binding MRNA Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Metabolic Process RNA Splicing Aminoacyl-tRNA Synthetase Multienzyme Complex Negative Regulation Of Stress-activated Protein Kinase Signaling Cascade Negative Regulation Of Stress-activated MAPK Cascade Nucleic Acid Metabolic Process Nuclear Speck MRNA Processing Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Nucleic Acid Binding MRNA Metabolic Process Negative Regulation Of Metabolic Process MRNA Splice Site Recognition TRNA Aminoacylation For Protein Translation Regulation Of Stress-activated Protein Kinase Signaling Cascade Aminoacyl-tRNA Ligase Activity TRNA Aminoacylation Regulation Of Stress-activated MAPK Cascade RNA Processing Protein Kinase Inhibitor Activity Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Gene Expression
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