UTF1 and SOX10

Number of citations of the paper that reports this interaction (PMID 16582099)
41

Data Source:
HPRD (two hybrid, in vitro)

		UTF1	SOX10
Gene Name		undifferentiated embryonic cell transcription factor 1	SRY (sex determining region Y)-box 10
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Extrinsic Component Of Mitochondrial Outer Membrane
	Molecular Function	Transcription Coactivator Activity Protein Binding HMG Box Domain Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Transcription Factor Binding Identical Protein Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Male Gonad Development Positive Regulation Of Transcription From RNA Polymerase II Promoter	In Utero Embryonic Development Neural Crest Cell Migration Positive Regulation Of Neuroblast Proliferation Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Peripheral Nervous System Development Anatomical Structure Morphogenesis Positive Regulation Of Gliogenesis Melanocyte Differentiation Negative Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Maturation Enteric Nervous System Development Digestive Tract Morphogenesis Developmental Growth Oligodendrocyte Differentiation Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: ATF2 SOX10 SOX8	28 interactors: ALX4 CDK6 CEBPA DLX5 EGR2 EXOC5 HHEX HIVEP1 HOXA3 HOXC4 JUN MEOX1 NMI OLIG2 PAX3 PAX6 POU3F2 POU3F3 POU5F1 PRRX1 PRRX2 SP1 SUMO1 SUMO2 SUMO3 TCF12 UBE2I UTF1
Entrez ID		8433	6663
HPRD ID		11964	03752
Ensembl ID		ENSG00000171794	ENSG00000100146
Uniprot IDs		Q5T230	B4DV62 P56693
PDB IDs
Enriched GO Terms of Interacting Partners?		Enteric Nervous System Development Adipose Tissue Development Autonomic Nervous System Development Neural Crest Cell Migration Positive Regulation Of Gliogenesis Neural Crest Cell Development Oligodendrocyte Differentiation Neural Crest Cell Differentiation Transcription From RNA Polymerase II Promoter Regulation Of Gliogenesis Peripheral Nervous System Development Mesenchymal Cell Development Fat Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Mesenchymal Cell Differentiation Cell Maturation Ameboidal-type Cell Migration Glial Cell Differentiation Positive Regulation Of Transcription, DNA-templated Mesenchyme Development Retinal Rod Cell Differentiation Positive Regulation Of Transforming Growth Factor Beta2 Production Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Gliogenesis Connective Tissue Development Positive Regulation Of Cellular Biosynthetic Process Stem Cell Development Renal Vesicle Induction Tissue Development Astrocyte Fate Commitment Metanephric Nephron Tubule Formation Negative Regulation Of Photoreceptor Cell Differentiation Regulation Of Transcription From RNA Polymerase II Promoter Stem Cell Differentiation Ureter Morphogenesis Metanephric Tubule Formation Positive Regulation Of Neurogenesis Regulation Of Transforming Growth Factor Beta2 Production Metanephric Nephron Tubule Morphogenesis Transcription, DNA-templated Tube Morphogenesis RNA Biosynthetic Process Anatomical Structure Morphogenesis Positive Regulation Of Cellular Metabolic Process Intra-S DNA Damage Checkpoint Positive Regulation Of Osteoblast Proliferation Positive Regulation Of Cell Development In Utero Embryonic Development Epithelial Cell Differentiation	Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Organ Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Tissue Development Regulation Of Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated RNA Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Gene Expression Positive Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process System Development Macromolecule Biosynthetic Process Protein Sumoylation Embryonic Morphogenesis Anatomical Structure Development Embryonic Organ Development Embryo Development Nucleobase-containing Compound Metabolic Process Multicellular Organismal Development Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Developmental Process Cellular Nitrogen Compound Metabolic Process Pattern Specification Process Embryonic Organ Morphogenesis Organ Morphogenesis Biosynthetic Process Nitrogen Compound Metabolic Process Positive Regulation Of Cell Proliferation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cellular Metabolic Process Regulation Of Cell Proliferation Gland Development
Tagcloud ?		abbreviated biochemically chimaeras chimaeric classically cooperatively demethylase derepression execute execution hampers ipsc ipscs kdm6a opted osk oskm pgcs pluripotency pluripotent pou5f1 primordial reprogram reprogramming robustly safeguards sall1 sall4 utx	abundantly border commences complexity crest dimethylation distinguishing foxd3 methyltransferase methyltransferases migratory msx1 multipotent neural neurepithelium nevertheless nsd3 plate precursors premigratory requirement revealing snail2 sox9 spatiotemporally specification stationary temporally unexpected
Tagcloud (Difference) ?		abbreviated biochemically chimaeras chimaeric classically cooperatively demethylase derepression execute execution hampers ipsc ipscs kdm6a opted osk oskm pgcs pluripotency pluripotent pou5f1 primordial reprogram reprogramming robustly safeguards sall1 sall4 utx	abundantly border commences complexity crest dimethylation distinguishing foxd3 methyltransferase methyltransferases migratory msx1 multipotent neural neurepithelium nevertheless nsd3 plate precursors premigratory requirement revealing snail2 sox9 spatiotemporally specification stationary temporally unexpected
Tagcloud (Intersection) ?