UTF1 and SOX8

Number of citations of the paper that reports this interaction (PMID 16582099)
41

Data Source:
HPRD (two hybrid)

		UTF1	SOX8
Gene Name		undifferentiated embryonic cell transcription factor 1	SRY (sex determining region Y)-box 8
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Cytoplasm Nuclear Transcription Factor Complex
	Molecular Function	Transcription Coactivator Activity Protein Binding HMG Box Domain Binding	RNA Polymerase II Core Promoter Sequence-specific DNA Binding Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity DNA Binding Transcription Factor Binding Protein Heterodimerization Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Male Gonad Development Positive Regulation Of Transcription From RNA Polymerase II Promoter	Osteoblast Differentiation In Utero Embryonic Development Neural Crest Cell Migration Transcription From RNA Polymerase II Promoter Signal Transduction Spermatogenesis Peripheral Nervous System Development Male Gonad Development Regulation Of Hormone Levels Positive Regulation Of Gliogenesis Positive Regulation Of Osteoblast Proliferation Skeletal Muscle Cell Differentiation Negative Regulation Of Apoptotic Process Cell Fate Commitment Fat Cell Differentiation Negative Regulation Of Myoblast Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Photoreceptor Cell Differentiation Cell Maturation Enteric Nervous System Development Oligodendrocyte Differentiation Sertoli Cell Development Astrocyte Fate Commitment Retina Development In Camera-type Eye Retinal Rod Cell Differentiation Adipose Tissue Development Morphogenesis Of A Branching Epithelium Renal Vesicle Induction Ureter Morphogenesis Metanephric Nephron Tubule Formation Positive Regulation Of Kidney Development Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis
Pathways
Drugs
Diseases
GWAS			Multiple sclerosis ( 21833088)
Protein-Protein Interactions		3 interactors: ATF2 SOX10 SOX8	18 interactors: CEBPA DLX5 EGR2 HHEX HOXC11 JAM2 JUN MMP1 NOD1 NR5A1 OLIG2 PAX3 PIDD1 POU3F3 POU5F1 SP1 TCF12 UTF1
Entrez ID		8433	30812
HPRD ID		11964	16175
Ensembl ID		ENSG00000171794	ENSG00000005513
Uniprot IDs		Q5T230	P57073
PDB IDs
Enriched GO Terms of Interacting Partners?		Enteric Nervous System Development Adipose Tissue Development Autonomic Nervous System Development Neural Crest Cell Migration Positive Regulation Of Gliogenesis Neural Crest Cell Development Oligodendrocyte Differentiation Neural Crest Cell Differentiation Transcription From RNA Polymerase II Promoter Regulation Of Gliogenesis Peripheral Nervous System Development Mesenchymal Cell Development Fat Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Mesenchymal Cell Differentiation Cell Maturation Ameboidal-type Cell Migration Glial Cell Differentiation Positive Regulation Of Transcription, DNA-templated Mesenchyme Development Retinal Rod Cell Differentiation Positive Regulation Of Transforming Growth Factor Beta2 Production Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Gliogenesis Connective Tissue Development Positive Regulation Of Cellular Biosynthetic Process Stem Cell Development Renal Vesicle Induction Tissue Development Astrocyte Fate Commitment Metanephric Nephron Tubule Formation Negative Regulation Of Photoreceptor Cell Differentiation Regulation Of Transcription From RNA Polymerase II Promoter Stem Cell Differentiation Ureter Morphogenesis Metanephric Tubule Formation Positive Regulation Of Neurogenesis Regulation Of Transforming Growth Factor Beta2 Production Metanephric Nephron Tubule Morphogenesis Transcription, DNA-templated Tube Morphogenesis RNA Biosynthetic Process Anatomical Structure Morphogenesis Positive Regulation Of Cellular Metabolic Process Intra-S DNA Damage Checkpoint Positive Regulation Of Osteoblast Proliferation Positive Regulation Of Cell Development In Utero Embryonic Development Epithelial Cell Differentiation	Positive Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Organ Development Regulation Of Gene Expression RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process System Development Cell Differentiation Tissue Development Nucleobase-containing Compound Metabolic Process Multicellular Organismal Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Anatomical Structure Development Cellular Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Gland Development Developmental Process Nitrogen Compound Metabolic Process Regulation Of Cellular Process Liver Development Embryonic Morphogenesis Anatomical Structure Formation Involved In Morphogenesis Embryo Development Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Pattern Specification Process Embryonic Organ Development Positive Regulation By Host Of Viral Transcription Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Myeloid Cell Differentiation Heart Development Endoderm Development
Tagcloud ?		abbreviated biochemically chimaeras chimaeric classically cooperatively demethylase derepression execute execution hampers ipsc ipscs kdm6a opted osk oskm pgcs pluripotency pluripotent pou5f1 primordial reprogram reprogramming robustly safeguards sall1 sall4 utx	adipocytes anabolic anesthesia cattle chronically coexpression coincident covering dorsi false implant intramuscular ld longissimus mid myofiber neuropeptide oxt oxtr oxytocin positives profiled reflecting revalor satellite steroid trenbolone twitch unexpectedly
Tagcloud (Difference) ?		abbreviated biochemically chimaeras chimaeric classically cooperatively demethylase derepression execute execution hampers ipsc ipscs kdm6a opted osk oskm pgcs pluripotency pluripotent pou5f1 primordial reprogram reprogramming robustly safeguards sall1 sall4 utx	adipocytes anabolic anesthesia cattle chronically coexpression coincident covering dorsi false implant intramuscular ld longissimus mid myofiber neuropeptide oxt oxtr oxytocin positives profiled reflecting revalor satellite steroid trenbolone twitch unexpectedly
Tagcloud (Intersection) ?