YTHDF1 and KRTAP7-1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		YTHDF1	KRTAP7-1
Description		YTH N6-methyladenosine RNA binding protein F1	keratin associated protein 7-1
Image			No pdb structure
GO Annotations	Cellular Component	P-body Cytoplasm Cytoplasmic Stress Granule	Intermediate Filament
	Molecular Function	RNA Binding MRNA Binding Protein Binding Ribosome Binding N6-methyladenosine-containing RNA Reader Activity	Protein Binding
	Biological Process	Immune System Process Regulation Of Antigen Processing And Presentation Learning Memory Stress Granule Assembly Regulation Of MRNA Stability Positive Regulation Of Translation Positive Regulation Of Translational Initiation MRNA Destabilization Organelle Assembly Regulation Of Long-term Synaptic Potentiation Regulation Of Axon Guidance
Pathways
Drugs
Diseases
GWAS		Response to cytadine analogues (cytosine arabinoside) ( 24483146)
Interacting Genes		42 interacting genes: ABHD11 BATF2 BICD2 C6orf15 CFTR CLK2 CPSF7 CTTN DMRTB1 DYNC1I1 ERI3 FAM168A FHIT HEY1 HSF4 ITSN2 KRTAP13-1 KRTAP26-1 KRTAP7-1 KRTAP8-1 LASP1 MAGED1 MOV10 MSX2 OIP5 PPIL3 PRR32 PRRC2B QKI RBFOX2 RBM22 RBMS3 RBPMS SARNP SF1 SNCA SNRPA TLE5 TMED9 VPS37C XRN2 ZNF34	37 interacting genes: ARID5A C11orf16 C1orf94 CELF5 CREB5 CRYBA2 DTX2 FAM168A FOXH1 GATA2 GCM2 HGS HNRNPF MKRN3 MYOZ3 OTX1 PITX1 PITX2 PRR13 PSMB1 RANBP3 RHOXF2 RNF38 ROR2 SHARPIN SMARCC1 SNRPC SPAG8 TCF7L2 TEKT4 TFAP2D TLE5 TLX3 TOLLIP VPS37C YTHDF1 ZIC1
Entrez ID		54915	337878
HPRD ID		11691	19546
Ensembl ID		ENSG00000149658	ENSG00000274749
Uniprot IDs		Q9BYJ9	Q8IUC3
PDB IDs		4RCI 4RCJ 7PCU 7QKN 7QL7 7YYE 7YYF 7YYJ 7YZ8 8BS4
Enriched GO Terms of Interacting Partners?		Nucleic Acid Binding MRNA Processing RNA Binding Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome MRNA Metabolic Process Negative Regulation Of Biosynthetic Process RNA Processing RNA Splicing, Via Transesterification Reactions RNA Splicing MRNA Binding	DNA-binding Transcription Factor Activity DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Sequence-specific Double-stranded DNA Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Transcription Regulator Complex Positive Regulation Of RNA Metabolic Process Chromatin Myoblast Fate Commitment Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of Macromolecule Biosynthetic Process Pituitary Gland Development Nucleus Positive Regulation Of Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Embryonic Morphogenesis Gland Development GABAergic Neuron Differentiation DNA Binding Inner Ear Morphogenesis Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Sequence-specific DNA Binding Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Androgen Receptor Signaling Pathway Regulation Of Macromolecule Biosynthetic Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding Axonemal A Tubule Inner Sheath Nuclear Androgen Receptor Binding Ubiquitin Binding Protein Binding R-SMAD Binding Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Embryonic Hindlimb Morphogenesis Regulation Of Metabolic Process Diencephalon Morphogenesis Superior Vena Cava Morphogenesis Subthalamic Nucleus Development Multivesicular Body Assembly MRNA Splice Site Recognition Multivesicular Body Organization
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