YTHDF1 and C6orf15

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		YTHDF1	C6orf15
Description		YTH N6-methyladenosine RNA binding protein F1	chromosome 6 open reading frame 15
Image			No pdb structure
GO Annotations	Cellular Component	P-body Cytoplasm Cytoplasmic Stress Granule	Extracellular Region Extracellular Matrix
	Molecular Function	RNA Binding MRNA Binding Protein Binding Ribosome Binding N6-methyladenosine-containing RNA Reader Activity	Protein Binding
	Biological Process	Immune System Process Regulation Of Antigen Processing And Presentation Learning Memory Stress Granule Assembly Regulation Of MRNA Stability Positive Regulation Of Translation Positive Regulation Of Translational Initiation MRNA Destabilization Organelle Assembly Regulation Of Long-term Synaptic Potentiation Regulation Of Axon Guidance	Extracellular Matrix Organization
Pathways
Drugs
Diseases
GWAS		Response to cytadine analogues (cytosine arabinoside) ( 24483146)	A body shape index ( 34021172) Apolipoprotein B levels ( 32203549) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Epstein-Barr virus immune response (EBNA-1) ( 23326239) Follicular lymphoma ( 20639881) Graves' disease ( 21841780) Hematology traits ( 23263863) Hip circumference adjusted for BMI ( 34021172) Hypothyroidism ( 22493691) Inflammatory bowel disease ( 28067908) Leprosy ( 32421744) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Malaria ( 31844061) Nickel levels ( 26025379) Response to hepatitis B vaccine ( 29534301) Rosacea symptom severity ( 29771307) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848) Small cell lung carcinoma ( 28604730) Thyrotoxic hypokalemic periodic paralysis and Graves disease ( 31050781) Type 1 diabetes (age at diagnosis) ( 33179336) Ulcerative colitis ( 28067908) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) White blood cell count ( 21738480)
Interacting Genes		42 interacting genes: ABHD11 BATF2 BICD2 C6orf15 CFTR CLK2 CPSF7 CTTN DMRTB1 DYNC1I1 ERI3 FAM168A FHIT HEY1 HSF4 ITSN2 KRTAP13-1 KRTAP26-1 KRTAP7-1 KRTAP8-1 LASP1 MAGED1 MOV10 MSX2 OIP5 PPIL3 PRR32 PRRC2B QKI RBFOX2 RBM22 RBMS3 RBPMS SARNP SF1 SNCA SNRPA TLE5 TMED9 VPS37C XRN2 ZNF34	5 interacting genes: KRTAP6-2 PROP1 UBQLN2 VENTX YTHDF1
Entrez ID		54915	29113
HPRD ID		11691	12856
Ensembl ID		ENSG00000149658	ENSG00000204542
Uniprot IDs		Q9BYJ9	M1T2K5 Q6UXA7
PDB IDs		4RCI 4RCJ 7PCU 7QKN 7QL7 7YYE 7YYF 7YYJ 7YZ8 8BS4
Enriched GO Terms of Interacting Partners?		Nucleic Acid Binding MRNA Processing RNA Binding Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome MRNA Metabolic Process Negative Regulation Of Biosynthetic Process RNA Processing RNA Splicing, Via Transesterification Reactions RNA Splicing MRNA Binding
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