YTHDF1 and RBMS3

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		YTHDF1	RBMS3
Description		YTH N6-methyladenosine RNA binding protein F1	RNA binding motif single stranded interacting protein 3
Image			No pdb structure
GO Annotations	Cellular Component	P-body Cytoplasm Cytoplasmic Stress Granule	Nucleus Cytoplasm Cytosol Ribonucleoprotein Complex
	Molecular Function	RNA Binding MRNA Binding Protein Binding Ribosome Binding N6-methyladenosine-containing RNA Reader Activity	Nucleic Acid Binding RNA Binding MRNA 3'-UTR Binding Poly(A) Binding Poly(U) RNA Binding MRNA 3'-UTR AU-rich Region Binding
	Biological Process	Immune System Process Regulation Of Antigen Processing And Presentation Learning Memory Stress Granule Assembly Regulation Of MRNA Stability Positive Regulation Of Translation Positive Regulation Of Translational Initiation MRNA Destabilization Organelle Assembly Regulation Of Long-term Synaptic Potentiation Regulation Of Axon Guidance	Defense Response To Tumor Cell Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Translation Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Response to cytadine analogues (cytosine arabinoside) ( 24483146)	Anti-saccade response ( 29064472) Antisaccade task score ( 31596458) Basal ganglia growth ( 29682794) Bipolar disorder ( 33169155) Bone mineral density ( 17903296) Breast size ( 22747683) Central corneal thickness ( 32528159) Chronic obstructive pulmonary disease ( 30804561) Cleft lip with or without cleft palate (maternal periconceptional alcohol intake interaction) ( 29535761) Dental caries ( 23259602) Dental caries (decayed and filled deciduous tooth surfaces) ( 31533690) Diastolic blood pressure ( 30224653) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Heel bone mineral density ( 30598549) Height ( 28552196) Intracranial aneurysm ( 29531279) Lung cancer in ever smokers ( 28604730) Lung function (FEV1/FVC) ( 30061609 30804560) Macular thickness ( 30535121) Major depressive disorder ( 29317602) Medication use (antihistamines for systemic use) ( 31015401) Night sleep phenotypes ( 27126917) Nonunion in individuals with fractures ( 30680360) Periodontal disease-related phenotype (Socransky) ( 26962152) Post bronchodilator FEV1 in COPD ( 26634245) Refractive error ( 32231278) Response to radiotherapy in cancer (late toxicity) ( 24785509) Schizophrenia ( 30285260)
Interacting Genes		42 interacting genes: ABHD11 BATF2 BICD2 C6orf15 CFTR CLK2 CPSF7 CTTN DMRTB1 DYNC1I1 ERI3 FAM168A FHIT HEY1 HSF4 ITSN2 KRTAP13-1 KRTAP26-1 KRTAP7-1 KRTAP8-1 LASP1 MAGED1 MOV10 MSX2 OIP5 PPIL3 PRR32 PRRC2B QKI RBFOX2 RBM22 RBMS3 RBPMS SARNP SF1 SNCA SNRPA TLE5 TMED9 VPS37C XRN2 ZNF34	1 interacting genes: YTHDF1
Entrez ID		54915	27303
HPRD ID		11691	16155
Ensembl ID		ENSG00000149658	ENSG00000144642
Uniprot IDs		Q9BYJ9	C9JIJ9 Q6XE24
PDB IDs		4RCI 4RCJ 7PCU 7QKN 7QL7 7YYE 7YYF 7YYJ 7YZ8 8BS4
Enriched GO Terms of Interacting Partners?		Nucleic Acid Binding MRNA Processing RNA Binding Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome MRNA Metabolic Process Negative Regulation Of Biosynthetic Process RNA Processing RNA Splicing, Via Transesterification Reactions RNA Splicing MRNA Binding	N6-methyladenosine-containing RNA Reader Activity Regulation Of Axon Guidance Regulation Of Antigen Processing And Presentation Regulation Of Long-term Synaptic Potentiation Stress Granule Assembly Positive Regulation Of Translational Initiation Regulation Of Translational Initiation Positive Regulation Of MRNA Catabolic Process MRNA Destabilization RNA Destabilization P-body Cytoplasmic Stress Granule Ribosome Binding Memory Learning Positive Regulation Of MRNA Metabolic Process Positive Regulation Of Translation
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