UTP23 and DDX52

Number of citations of the paper that reports this interaction (PubMedID 28082392)
37

Data Source:
BioGRID (pull down)

		UTP23	DDX52
Description		UTP23 small subunit processome component	DExD-box helicase 52
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Small-subunit Processome	Nucleus Nucleoplasm Nucleolus Membrane
	Molecular Function	RNA Binding MRNA 3'-UTR Binding Protein Binding MRNA 5'-UTR Binding Small Ribosomal Subunit RRNA Binding	Nucleotide Binding Nucleic Acid Binding RNA Binding RNA Helicase Activity Helicase Activity ATP Binding Hydrolase Activity ATP Hydrolysis Activity
	Biological Process	Endonucleolytic Cleavage In 5'-ETS Of Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Processing Ribosome Biogenesis	Maturation Of SSU-rRNA
Pathways			rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS			Ovarian cancer ( 23535730)
Interacting Genes		31 interacting genes: APP CYSRT1 DDX52 FCF1 GOLGA2 GRN KRT31 KRT34 KRT38 KRT40 KRTAP1-3 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-3 MEOX2 MID2 NBPF19 NFKBID NHP2 NOTCH2NLA PDE9A RRP7A SNHG3 TCF4 TEPSIN TRAF2 TRIB3 TRIM23 TRIM27	5 interacting genes: AP4M1 HLCS MTNR1A PMP22 UTP23
Entrez ID		84294	11056
HPRD ID		17499	09911
Ensembl ID		ENSG00000147679	ENSG00000278053
Uniprot IDs		Q9BRU9	B3KM65 Q9Y2R4
PDB IDs			3DKP
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament Structural Constituent Of Skin Epidermis Intermediate Filament Organization Astrocyte Activation Involved In Immune Response Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Identical Protein Binding Supramolecular Fiber Organization Structural Molecule Activity Negative Regulation Of Viral Transcription Suppression Of Viral Release By Host Astrocyte Activation Regulation Of Autophagy RRNA Processing Regulation Of Viral Transcription	Biotin--[biotin Carboxyl-carrier Protein] Ligase Activity Biotin Metabolic Process Response To Biotin Melatonin Receptor Activity Compact Myelin Protein Localization To Basolateral Plasma Membrane AP-4 Adaptor Complex Biotin Binding Small Ribosomal Subunit RRNA Binding Endonucleolytic Cleavage In 5'-ETS Of Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Bleb Assembly Golgi To Lysosome Transport Clathrin Adaptor Complex Nuclear Lamina Golgi To Endosome Transport Myelin Assembly Hormone Binding Endonucleolytic Cleavage Of Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA)
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