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DDX52

Description DExD-box helicase 52
Image
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Nucleolus
  • Membrane
Molecular Function
  • Nucleotide Binding
  • Nucleic Acid Binding
  • RNA Binding
  • RNA Helicase Activity
  • Helicase Activity
  • ATP Binding
  • Hydrolase Activity
  • ATP Hydrolysis Activity
Biological Process
  • Maturation Of SSU-rRNA
Pathways
  • rRNA modification in the nucleus and cytosol
  • Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS
  • Ovarian cancer ( 23535730)
Interacting Genes 5 interacting genes: AP4M1 HLCS MTNR1A PMP22 UTP23
Entrez ID 11056
HPRD ID 09911
Ensembl ID ENSG00000278053
Uniprot IDs B3KM65 Q9Y2R4
PDB IDs 3DKP
Enriched GO Terms of Interacting Partners?
  • Biotin--[biotin Carboxyl-carrier Protein] Ligase Activity
  • Biotin Metabolic Process
  • Response To Biotin
  • Melatonin Receptor Activity
  • Compact Myelin
  • Protein Localization To Basolateral Plasma Membrane
  • AP-4 Adaptor Complex
  • Biotin Binding
  • Small Ribosomal Subunit RRNA Binding
  • Endonucleolytic Cleavage In 5'-ETS Of Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA)
  • Bleb Assembly
  • Golgi To Lysosome Transport
  • Clathrin Adaptor Complex
  • Nuclear Lamina
  • Golgi To Endosome Transport
  • Myelin Assembly
  • Hormone Binding
  • Endonucleolytic Cleavage Of Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA)
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© Madhavi K. Ganapathiraju 2012-2025