STK24 and PDCD10

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		STK24	PDCD10
Gene Name		serine/threonine kinase 24	programmed cell death 10
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Membrane Extracellular Vesicular Exosome	Golgi Membrane Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Receptor Signaling Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Metal Ion Binding	Protein Binding Protein Kinase Binding Protein Homodimerization Activity Protein N-terminus Binding
	Biological Process	Protein Phosphorylation Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Signal Transduction Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Signal Transduction By Phosphorylation Negative Regulation Of Cell Migration Response To Hydrogen Peroxide Protein Autophosphorylation Regulation Of Axon Regeneration Execution Phase Of Apoptosis	Angiogenesis Positive Regulation Of Cell Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Cell Migration Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Rho Protein Signal Transduction Intrinsic Apoptotic Signaling Pathway In Response To Hydrogen Peroxide Response To Hydrogen Peroxide Negative Regulation Of Apoptotic Process Stress Fiber Assembly Positive Regulation Of MAP Kinase Activity Wound Healing, Spreading Of Cells Positive Regulation Of Notch Signaling Pathway Protein Stabilization Establishment Of Golgi Localization Positive Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Golgi Reassembly Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis
Pathways		Apoptotic cleavage of cellular proteins Programmed Cell Death Apoptotic execution phase
Drugs
Diseases
GWAS		Alzheimer's disease ( 22159054) Educational attainment ( 23722424) Longevity ( 20834067)
Protein-Protein Interactions		11 interactors: CASP3 CASP7 CASP8 LRRK2 NEDD4 PDCD10 STK38L SUMO1 SUMO2 SUMO3 VAV2	5 interactors: C4orf19 CHMP5 STK24 STK25 STK26
Entrez ID		8428	11235
HPRD ID		10385	10141
Ensembl ID		ENSG00000102572	ENSG00000114209
Uniprot IDs		B4DR80 Q5U0E6 Q6P0Y1 Q9Y6E0	Q9BUL8
PDB IDs		3A7F 3A7G 3A7H 3A7I 3A7J 3CKW 3CKX 3ZHP	3AJM 3L8I 3L8J 3RQE 3RQF 3RQG 3W8H 3W8I 4GEH
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Proteolysis Positive Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Proteolysis Regulation Of Protein Metabolic Process Positive Regulation Of Protein Catabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Protein Sumoylation Apoptotic Signaling Pathway Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Intrinsic Apoptotic Signaling Pathway Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Cell Death Death Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Proteasomal Protein Catabolic Process Intracellular Signal Transduction Positive Regulation Of Cell Death Execution Phase Of Apoptosis Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Zymogen Activation Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Catalytic Activity Cardiovascular System Development Regulation Of Cell Death Positive Regulation Of Endopeptidase Activity Blood Vessel Morphogenesis Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Peptidase Activity Apoptotic Process Signal Transduction Response To Inorganic Substance Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Programmed Cell Death Positive Regulation Of Hydrolase Activity Protein Localization To Organelle Blood Vessel Development Protein Metabolic Process Vasculature Development Cellular Response To Organic Substance Regulation Of Metabolic Process	Response To Hydrogen Peroxide Response To Reactive Oxygen Species Protein Autophosphorylation Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Response To Oxidative Stress Response To Inorganic Substance Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Execution Phase Of Apoptosis Apoptotic Process Programmed Cell Death Intrinsic Apoptotic Signaling Pathway In Response To Hydrogen Peroxide Cell Death Death Intrinsic Apoptotic Signaling Pathway Cellular Response To Oxidative Stress Golgi Reassembly Protein Phosphorylation Signal Transduction By Phosphorylation Establishment Of Golgi Localization Establishment Of Organelle Localization Golgi Inheritance Apoptotic Signaling Pathway Regulation Of Mitotic Spindle Assembly Regulation Of Neuron Projection Development Golgi Localization Regulation Of Spindle Assembly Organelle Localization Phosphorylation Regulation Of Cellular Component Organization Regulation Of Hydrogen Peroxide-induced Cell Death Regulation Of Mitotic Spindle Organization Regulation Of Cell Projection Organization Microvillus Assembly Microvillus Organization Regulation Of Neuron Differentiation Regulation Of Axon Regeneration Cell Separation After Cytokinesis Mitotic Metaphase Plate Congression Regulation Of Receptor Recycling Regulation Of Neurogenesis Regulation Of Response To Reactive Oxygen Species Endosome To Lysosome Transport Metaphase Plate Congression Phosphate-containing Compound Metabolic Process Regulation Of Centrosome Duplication Establishment Of Chromosome Localization Regulation Of Cell Development Lysosomal Transport Regulation Of Centrosome Cycle Regulation Of Cellular Response To Oxidative Stress
Tagcloud ?		asset atxn1 atxn2 atxn3 atxn7 bioinformatic c5orf42 cacna1a cag celf2 crebbp ebf1 enriches melanogenesis moving nfia paxip1 plekhg4 polyq ppp2r2b sca screens spinocerebellar srsf4 tbp tremendous uguuu utrs ywhag	4b adriamycin ataxia carboplatin coded ct cyclophosphamide desirable eif4b isoaspartate matr3 matrin meiotic microrchidia morc3 pbl pbls pcmtd2 personalised psmb1 rmnd5a runt runx2 sacm1l subtraction telangiectasia tmem66 undesired znf644
Tagcloud (Difference) ?		asset atxn1 atxn2 atxn3 atxn7 bioinformatic c5orf42 cacna1a cag celf2 crebbp ebf1 enriches melanogenesis moving nfia paxip1 plekhg4 polyq ppp2r2b sca screens spinocerebellar srsf4 tbp tremendous uguuu utrs ywhag	4b adriamycin ataxia carboplatin coded ct cyclophosphamide desirable eif4b isoaspartate matr3 matrin meiotic microrchidia morc3 pbl pbls pcmtd2 personalised psmb1 rmnd5a runt runx2 sacm1l subtraction telangiectasia tmem66 undesired znf644
Tagcloud (Intersection) ?