STK24

Gene Name		serine/threonine kinase 24
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Receptor Signaling Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Metal Ion Binding
	Biological Process	Protein Phosphorylation Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Signal Transduction Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Signal Transduction By Phosphorylation Negative Regulation Of Cell Migration Response To Hydrogen Peroxide Protein Autophosphorylation Regulation Of Axon Regeneration Execution Phase Of Apoptosis
Pathways		Apoptotic cleavage of cellular proteins Programmed Cell Death Apoptotic execution phase
Drugs
Diseases
GWAS		Alzheimer's disease ( 22159054) Educational attainment ( 23722424) Longevity ( 20834067)
Protein-protein Interactions		11 interactors: CASP3 CASP7 CASP8 LRRK2 NEDD4 PDCD10 STK38L SUMO1 SUMO2 SUMO3 VAV2
Entrez ID		8428
HPRD ID		10385
Ensembl ID		ENSG00000102572
Uniprot IDs		B4DR80 Q5U0E6 Q6P0Y1 Q9Y6E0
PDB IDs		3A7F 3A7G 3A7H 3A7I 3A7J 3CKW 3CKX 3ZHP
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Proteolysis Positive Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Proteolysis Regulation Of Protein Metabolic Process Positive Regulation Of Protein Catabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Protein Sumoylation Apoptotic Signaling Pathway Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Intrinsic Apoptotic Signaling Pathway Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Cell Death Death Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Proteasomal Protein Catabolic Process Intracellular Signal Transduction Positive Regulation Of Cell Death Execution Phase Of Apoptosis Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Zymogen Activation Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Catalytic Activity Cardiovascular System Development Regulation Of Cell Death Positive Regulation Of Endopeptidase Activity Blood Vessel Morphogenesis Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Peptidase Activity Apoptotic Process Signal Transduction Response To Inorganic Substance Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Programmed Cell Death Positive Regulation Of Hydrolase Activity Protein Localization To Organelle Blood Vessel Development Protein Metabolic Process Vasculature Development Cellular Response To Organic Substance Regulation Of Metabolic Process
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