PDCD10 and STK24

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
HPRD (two hybrid)

		PDCD10	STK24
Description		programmed cell death 10	serine/threonine kinase 24
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GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Membrane Extracellular Exosome FAR/SIN/STRIPAK Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytosol Membrane Extracellular Exosome FAR/SIN/STRIPAK Complex
	Molecular Function	Protein Binding Protein Kinase Binding Protein Homodimerization Activity	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Cadherin Binding Metal Ion Binding Protein Serine Kinase Activity
	Biological Process	Angiogenesis Endothelium Development Apoptotic Process Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Cell Migration Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Rho Protein Signal Transduction Intracellular Signal Transduction Intrinsic Apoptotic Signaling Pathway In Response To Hydrogen Peroxide Negative Regulation Of Apoptotic Process Stress Fiber Assembly Positive Regulation Of MAP Kinase Activity Wound Healing, Spreading Of Cells Positive Regulation Of Notch Signaling Pathway Regulation Of Angiogenesis Protein Stabilization Establishment Of Golgi Localization Positive Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Golgi Reassembly Positive Regulation Of Intracellular Protein Transport Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Cellular Response To Leukemia Inhibitory Factor	Protein Phosphorylation Apoptotic Process Signal Transduction Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Cellular Response To Starvation Negative Regulation Of Cell Migration Cellular Response To Oxidative Stress Intracellular Signal Transduction Protein Autophosphorylation Regulation Of Axon Regeneration Execution Phase Of Apoptosis
Pathways			Apoptotic cleavage of cellular proteins Apoptotic execution phase
Drugs			Fostamatinib
Diseases		Cerebral cavernous malformation
GWAS		Fast beta electroencephalogram ( 28070124) Platelet count ( 32888494)	Adult body size ( 32376654) Adventurousness ( 30643258) Alzheimer's disease ( 22159054) Educational attainment ( 23722424 25201988) Gastroesophageal reflux disease ( 34187846) General factor of neuroticism ( 30867560) General risk tolerance (MTAG) ( 30643258) Household income (MTAG) ( 31844048) Longevity ( 20834067) Methadone dose in opioid dependence ( 28115739) Mood instability ( 31168069) Reading disability or specific language impairment (pleiotropy) ( 25065397) Shoulder impingement or rotator cuff tear ( 33482370) Triglyceride levels ( 32203549) Urinary sodium excretion ( 31409800)
Interacting Genes		9 interacting genes: CHMP5 FAM118B FARSA FRYL MINAR1 PLEKHS1 STK24 STK25 STRN	12 interacting genes: CAB39 CASP3 CASP7 CASP8 ERBB2 LRRK2 NEDD4 OGT PDCD10 STK11 STK38L VAV2
Entrez ID		11235	8428
HPRD ID		10141	10385
Ensembl ID		ENSG00000114209	ENSG00000102572
Uniprot IDs		Q9BUL8	B4DR80 Q5U0E6 Q6P0Y1 Q9Y6E0
PDB IDs		3AJM 3L8I 3L8J 3RQE 3RQF 3RQG 3W8H 3W8I 4GEH 4TVQ	3A7F 3A7G 3A7H 3A7I 3A7J 3CKW 3CKX 3ZHP 4O27 4QML 4QMM 4QMN 4QMO 4QMP 4QMQ 4QMS 4QMT 4QMU 4QMV 4QMW 4QMX 4QMY 4QMZ 4QNA 4QO9 4U8Z 4W8D 4W8E 7B30 7B31 7B32 7B33 7B34 7B35 8BZI 8BZJ 8QLQ 8QLR 8QLS 8QLT
Enriched GO Terms of Interacting Partners?		FAR/SIN/STRIPAK Complex Regulation Of Neuron Projection Development Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Mitotic Cytokinetic Process Cytokinetic Process Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Angiotensin-mediated Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure Mitotic Cleavage Furrow Formation	Positive Regulation Of Protein Metabolic Process Intracellular Signal Transduction Pyroptotic Inflammatory Response Positive Regulation Of Signal Transduction Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Communication Positive Regulation Of Signaling Execution Phase Of Apoptosis Regulation Of Intracellular Signal Transduction Regulation Of Cellular Localization Cytosol Regulation Of Protein Metabolic Process Signal Transduction Neuromuscular Junction Development Protein Modification Process Cellular Response To Staurosporine Response To UV Regulation Of Autophagy Protein Processing Response To Anesthetic Death-inducing Signaling Complex Cysteine-type Endopeptidase Activity Positive Regulation Of Neuron Apoptotic Process Apoptotic Process Positive Regulation Of Pyroptotic Inflammatory Response Protein Metabolic Process Cell Death Regulation Of Programmed Cell Death Programmed Cell Death Response To Cobalt Ion Cytoplasm Regulation Of Signal Transduction Fibroblast Apoptotic Process Regulation Of Intracellular Transport Heart Development Response To Stress Cell Projection Organization Protein Localization To Organelle Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Protein Modification Process Golgi Localization Protein Maturation Response To Light Stimulus Apoptotic Signaling Pathway Response To Metal Ion Death Receptor Binding Positive Regulation Of Metabolic Process Regulation Of Cell Communication Regulation Of Signaling Protein Poly-ADP-ribosylation
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