RPAIN and GSTA1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		RPAIN	GSTA1
Description		RPA interacting protein	glutathione S-transferase alpha 1
Image		No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Cytoplasm PML Body	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding	Glutathione Transferase Activity Peroxidase Activity Glutathione Peroxidase Activity Steroid Delta-isomerase Activity Fatty Acid Binding Protein Binding Oxidoreductase Activity Transferase Activity Isomerase Activity
	Biological Process	Protein Import Into Nucleus Response To UV	Lipid Metabolic Process Prostaglandin Metabolic Process Glutathione Metabolic Process Xenobiotic Metabolic Process Epithelial Cell Differentiation Linoleic Acid Metabolic Process Cellular Oxidant Detoxification Glutathione Derivative Biosynthetic Process
Pathways			Glutathione conjugation Heme degradation Azathioprine ADME NFE2L2 regulating anti-oxidant/detoxification enzymes
Drugs			Glutathione S-Hydroxycysteine 2-Hydroxyethyl Disulfide N-(4-Aminobutanoyl)-S-(4-methoxybenzyl)-L-cysteinylglycine Glutathione sulfonic acid Glutathione disulfide S-benzylglutathione Deoxycholic acid S-Hexylglutathione Hypericin
Diseases
GWAS		Body mass index ( 29273807) Menopause (age at onset) ( 26414677) Neutrophil count ( 32888494) White blood cell count ( 32888494)	Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Platelet count ( 27863252 32888494) Plateletcrit ( 27863252 32888494) Serum alkaline phosphatase levels ( 33547301) Triglyceride levels ( 33339817)
Interacting Genes		7 interacting genes: ADH6 CDCA5 CLNK CYP17A1 GSTA1 RAD51B TNS4	7 interacting genes: APP GSTA2 LSM3 PPP2CB RPAIN ST3GAL1 YWHAE
Entrez ID		84268	2938
HPRD ID		14615	00708
Ensembl ID		ENSG00000129197	ENSG00000243955
Uniprot IDs		B3KTT3 Q86UA6	A0A140VJK4 B7Z1F9 P08263
PDB IDs			1GSD 1GSE 1GSF 1GUH 1K3L 1K3O 1K3Y 1LBK 1PKW 1PKZ 1PL1 1PL2 1USB 1XWG 1YDK 2R3X 2R6K 3I69 3I6A 3IK9 3KTL 3L0H 3Q74 3U6V 3ZFB 3ZFL 4HJ2 5JCU 5LCZ 5LD0 6ATO 6ATP 6ATQ 6ATR 6YAW 7BIB 7BIC 8BHC 8BHE
Enriched GO Terms of Interacting Partners?		Olefinic Compound Metabolic Process Steroid 17-alpha-monooxygenase Activity Hormone Metabolic Process Oxidoreductase Activity Cortisol Biosynthetic Process Glucocorticoid Biosynthetic Process Cortisol Metabolic Process Glutathione Derivative Biosynthetic Process Steroid Delta-isomerase Activity Blastocyst Growth Rad51B-Rad51C-Rad51D-XRCC2 Complex Mast Cell Granule	Response To Lead Ion Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Toll-like Receptor Signaling Pathway Regulation Of Response To Calcium Ion Trans-Golgi Network Membrane Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Golgi Medial Cisterna Membrane Negative Regulation Of Activated CD8-positive, Alpha-beta T Cell Apoptotic Process Protein Sialylation Beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide Alpha-2,3- Sialyltransferase Golgi Trans Cisterna Membrane Memory B Cell Differentiation Regulation Of Heart Rate By Hormone U6 SnRNA 3'-end Binding Regulation Of Calcium Ion Transmembrane Transport Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Cell Activation Involved In Immune Response Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Transmembrane Transporter Binding Ganglioside Biosynthetic Process Via Lactosylceramide Regulation Of Heart Rate By Chemical Signal Negative Regulation Of Calcium Ion Export Across Plasma Membrane Lsm1-7-Pat1 Complex Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Regulation Of Neurofibrillary Tangle Assembly
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