RPAIN and CDCA5

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		RPAIN	CDCA5
Description		RPA interacting protein	cell division cycle associated 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Cytoplasm PML Body	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding	Chromatin Binding Protein Binding Protein-containing Complex Binding
	Biological Process	Protein Import Into Nucleus Response To UV	Double-strand Break Repair Mitotic Sister Chromatid Cohesion Cell Division
Pathways			Separation of Sister Chromatids Establishment of Sister Chromatid Cohesion Resolution of Sister Chromatid Cohesion
Drugs
Diseases
GWAS		Body mass index ( 29273807) Menopause (age at onset) ( 26414677) Neutrophil count ( 32888494) White blood cell count ( 32888494)
Interacting Genes		7 interacting genes: ADH6 CDCA5 CLNK CYP17A1 GSTA1 RAD51B TNS4	9 interacting genes: CDK1 IRAK3 KDM1A NAA11 RPAIN SENP2 TTLL3 WAPL XRCC6
Entrez ID		84268	113130
HPRD ID		14615	13016
Ensembl ID		ENSG00000129197	ENSG00000146670
Uniprot IDs		B3KTT3 Q86UA6	Q96FF9
PDB IDs
Enriched GO Terms of Interacting Partners?		Olefinic Compound Metabolic Process Steroid 17-alpha-monooxygenase Activity Hormone Metabolic Process Oxidoreductase Activity Cortisol Biosynthetic Process Glucocorticoid Biosynthetic Process Cortisol Metabolic Process Glutathione Derivative Biosynthetic Process Steroid Delta-isomerase Activity Blastocyst Growth Rad51B-Rad51C-Rad51D-XRCC2 Complex Mast Cell Granule	Protein Modification Process Regulation Of DNA Metabolic Process Regulation Of DNA Replication Chromosome, Telomeric Region Telomeric DNA Binding Cellular Response To Gamma Radiation Cyclin Binding Nucleoplasm Negative Regulation Of Metabolic Process Pronuclear Fusion Mitotic DNA-templated DNA Replication Cyclin B1-CDK1 Complex Chromosome Organization Negative Regulation Of Macromolecule Metabolic Process Cyclin A1-CDK1 Complex Cyclin A2-CDK1 Complex Response To Gamma Radiation Positive Regulation Of Protein Modification Process Cellular Response To Ionizing Radiation Positive Regulation Of Macrophage Tolerance Induction Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity ATP-dependent Protein-DNA Unloader Activity Negative Regulation Of Chromatin Binding Protein-glycine Ligase Activity, Initiating Protein Polyglycylation Protein-glycine Ligase Activity Protein-N-terminal-alanine Acetyltransferase Activity Protein-N-terminal-glutamate Acetyltransferase Activity Protein Localization To Chromosome Protein Metabolic Process Mitotic DNA Replication Muscle Cell Development DNA Synthesis Involved In Mitotic DNA Replication Cyclin-dependent Protein Kinase Activity Response To Toxic Substance DNA End Binding Response To Radiation Ku70:Ku80 Complex Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of Protein Ubiquitination PML Body Protein N-terminal-serine Acetyltransferase Activity Protein Modification By Small Protein Removal Regulation Of Schwann Cell Differentiation Positive Regulation Of Mitochondrial ATP Synthesis Coupled Electron Transport Positive Regulation Of Post-translational Protein Modification Protein Demethylase Activity Regulation Of DNA Endoreduplication Nucleus
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