NFKBIE

Gene Name		nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding
	Biological Process	D-serine Transport Cytoplasmic Sequestering Of Transcription Factor
Pathways		Signaling by the B Cell Receptor (BCR) Downstream signaling events of B Cell Receptor (BCR) Activation of NF-kappaB in B cells Adaptive Immune System
Drugs
Diseases
GWAS		Rheumatoid arthritis ( 22446963 23028356)
Protein-protein Interactions		15 interactors: ANKHD1 C1QBP CUL1 HDAC4 HDAC5 IL1A JUP KBTBD7 NCOR2 NFKB1 NFKB2 PPP6C REL RELA SKP1
Entrez ID		4794
HPRD ID		05181
Ensembl ID		ENSG00000146232
Uniprot IDs		O00221 Q96F31
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Inflammatory Response Negative Regulation Of Transcription From RNA Polymerase II Promoter NIK/NF-kappaB Signaling Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Interleukin-12 Biosynthetic Process Regulation Of Interleukin-12 Production Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Defense Response Negative Regulation Of Biosynthetic Process Regulation Of Cytokine Production Regulation Of Cytokine Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Signal Transduction Positive Regulation Of Cellular Biosynthetic Process Notch Signaling Pathway Positive Regulation Of Cytokine Production Response To Cytokine Signaling Response To Organic Substance Positive Regulation Of Metabolic Process Cell Communication Positive Regulation Of Protein Metabolic Process Positive Regulation Of Transcription, DNA-templated Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Positive Regulation Of MiRNA Metabolic Process I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cytokine Biosynthetic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Immune System Process Regulation Of Protein Metabolic Process MyD88-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Interleukin-12 Biosynthetic Process Cellular Response To Nicotine Cellular Response To Stimulus
Tagcloud ?		1980s a20 acquire bearing budding ccl17 ccl22 cd23 cd40 cd40l cd80 chemoattractant chronically costimulatory cytidine deaminase humoral hypergammaglobulinemia issued lymphotoxin map2k1 messengers nfkb1 productively tnip1 tonsillar traf1 virions