TSSK1B and TSKS

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TSSK1B	TSKS
Description		testis specific serine kinase 1B	testis specific serine kinase substrate
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Cytoplasm Cilium Cytoplasmic Vesicle Motile Cilium Cell Projection	Cytoplasm Centriole Cytoskeleton
	Molecular Function	Nucleotide Binding Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein-containing Complex Binding Metal Ion Binding Protein Serine Kinase Activity	Protein Binding Protein Kinase Binding
	Biological Process	Protein Phosphorylation Spermatogenesis Spermatid Development Cell Differentiation
Pathways
Drugs		Fostamatinib
Diseases
GWAS			Urate levels ( 31578528)
Interacting Genes		8 interacting genes: CHEK2 EFS FAM229B FOXN1 MEOX2 TGFBR1 TGFBR2 TSKS	5 interacting genes: APP KRT27 TPM3 TSSK1B TSSK2
Entrez ID		83942	60385
HPRD ID		11610	09748
Ensembl ID		ENSG00000212122	ENSG00000126467
Uniprot IDs		A0ZT98 Q9BXA7	Q9UJT2
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Transforming Growth Factor Beta Ligand-receptor Complex Roof Of Mouth Development Activin Receptor Complex Activin Receptor Activity, Type I Transforming Growth Factor Beta Receptor Activity Regulation Of Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Positive Regulation Of Cardiac Epithelial To Mesenchymal Transition Blood Vessel Morphogenesis Activin Binding Transmembrane Receptor Protein Serine/threonine Kinase Activity Transforming Growth Factor Beta Binding Response To Cholesterol Embryonic Cranial Skeleton Morphogenesis Activin Receptor Signaling Pathway Ventricular Septum Morphogenesis Positive Regulation Of SMAD Protein Signal Transduction Tissue Development Lens Development In Camera-type Eye Thymus Development SMAD Binding Tube Morphogenesis Positive Regulation Of Epithelial To Mesenchymal Transition Regulation Of SMAD Protein Signal Transduction Artery Morphogenesis Cell Proliferation Involved In Endocardial Cushion Morphogenesis Positive Regulation Of Tolerance Induction To Self Antigen Superior Endocardial Cushion Morphogenesis Inferior Endocardial Cushion Morphogenesis Cardiac Septum Morphogenesis Embryonic Skeletal System Morphogenesis Epithelial To Mesenchymal Transition Tissue Morphogenesis Regulation Of Stem Cell Proliferation Protein Serine/threonine Kinase Activity Vascular Endothelial Cell Proliferation Epicardium Morphogenesis Hematopoietic Or Lymphoid Organ Development Bronchus Morphogenesis Transforming Growth Factor Beta Receptor Activity, Type II Positive Regulation Of B Cell Tolerance Induction Mammary Gland Morphogenesis Lymphoid Lineage Cell Migration Into Thymus Thymus Epithelium Morphogenesis Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Mesenchymal Cell Differentiation Regulation Of Epithelial To Mesenchymal Transition Skeletal System Morphogenesis Proepicardium Development	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Cell Development Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Supramolecular Fiber Organization Muscle Thin Filament Tropomyosin Magnesium Ion Binding Germ Cell Development Acrosomal Vesicle Spermatid Development Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Cellular Developmental Process Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding Golgi-associated Vesicle
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