TSKS and TSSK2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)
HPRD (in vivo, two hybrid)

		TSKS	TSSK2
Description		testis specific serine kinase substrate	testis specific serine kinase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centriole Cytoskeleton	Acrosomal Vesicle Nucleus Cytoplasm Centriole Cytoskeleton
	Molecular Function	Protein Binding Protein Kinase Binding	Nucleotide Binding Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein-containing Complex Binding Metal Ion Binding Protein Serine Kinase Activity
	Biological Process		Protein Phosphorylation Spermatogenesis Spermatid Development Cell Differentiation Protein Autophosphorylation
Pathways
Drugs
Diseases
GWAS		Urate levels ( 31578528)	Platelet aggregation ( 29185836)
Interacting Genes		5 interacting genes: APP KRT27 TPM3 TSSK1B TSSK2	8 interacting genes: APP FAM229B LZTS2 PTPRD SKIC2 TFG TSEN15 TSKS
Entrez ID		60385	23617
HPRD ID		09748	10255
Ensembl ID		ENSG00000126467	ENSG00000206203
Uniprot IDs		Q9UJT2	A0ZT99 Q96PF2
PDB IDs
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Cell Development Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Supramolecular Fiber Organization Muscle Thin Filament Tropomyosin Magnesium Ion Binding Germ Cell Development Acrosomal Vesicle Spermatid Development Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Cellular Developmental Process Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding Golgi-associated Vesicle	Acetylcholine Receptor Activator Activity Negative Regulation Of Protein Localization To Nucleus Negative Regulation Of Canonical Wnt Signaling Pathway Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Regulation Of Postsynapse Organization Lipoprotein Particle Regulation Of Protein Localization To Nucleus Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Developmental Growth Involved In Morphogenesis Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Ski Complex Nuclear-transcribed MRNA Catabolic Process, 3'-5' Exonucleolytic Nonsense-mediated Decay Primary Ureteric Bud Growth Regulation Of Synapse Assembly Regulation Of Spontaneous Synaptic Transmission Negative Regulation Of Wnt Signaling Pathway NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Trans-synaptic Signaling By Trans-synaptic Complex Cell Surface Receptor Protein Tyrosine Phosphatase Signaling Pathway 3'-5' RNA Helicase Activity Ureter Morphogenesis
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