TSSK1B and FAM229B

Number of citations of the paper that reports this interaction (PubMedID 32707033)
104

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		TSSK1B	FAM229B
Description		testis specific serine kinase 1B	family with sequence similarity 229 member B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Cytoplasm Cilium Cytoplasmic Vesicle Motile Cilium Cell Projection
	Molecular Function	Nucleotide Binding Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein-containing Complex Binding Metal Ion Binding Protein Serine Kinase Activity	Protein Binding
	Biological Process	Protein Phosphorylation Spermatogenesis Spermatid Development Cell Differentiation
Pathways
Drugs		Fostamatinib
Diseases
GWAS
Interacting Genes		8 interacting genes: CHEK2 EFS FAM229B FOXN1 MEOX2 TGFBR1 TGFBR2 TSKS	2 interacting genes: TSSK1B TSSK2
Entrez ID		83942	619208
HPRD ID		11610	18863
Ensembl ID		ENSG00000212122	ENSG00000203778
Uniprot IDs		A0ZT98 Q9BXA7	Q4G0N7
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Transforming Growth Factor Beta Ligand-receptor Complex Roof Of Mouth Development Activin Receptor Complex Activin Receptor Activity, Type I Transforming Growth Factor Beta Receptor Activity Regulation Of Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Positive Regulation Of Cardiac Epithelial To Mesenchymal Transition Blood Vessel Morphogenesis Activin Binding Transmembrane Receptor Protein Serine/threonine Kinase Activity Transforming Growth Factor Beta Binding Response To Cholesterol Embryonic Cranial Skeleton Morphogenesis Activin Receptor Signaling Pathway Ventricular Septum Morphogenesis Positive Regulation Of SMAD Protein Signal Transduction Tissue Development Lens Development In Camera-type Eye Thymus Development SMAD Binding Tube Morphogenesis Positive Regulation Of Epithelial To Mesenchymal Transition Regulation Of SMAD Protein Signal Transduction Artery Morphogenesis Cell Proliferation Involved In Endocardial Cushion Morphogenesis Positive Regulation Of Tolerance Induction To Self Antigen Superior Endocardial Cushion Morphogenesis Inferior Endocardial Cushion Morphogenesis Cardiac Septum Morphogenesis Embryonic Skeletal System Morphogenesis Epithelial To Mesenchymal Transition Tissue Morphogenesis Regulation Of Stem Cell Proliferation Protein Serine/threonine Kinase Activity Vascular Endothelial Cell Proliferation Epicardium Morphogenesis Hematopoietic Or Lymphoid Organ Development Bronchus Morphogenesis Transforming Growth Factor Beta Receptor Activity, Type II Positive Regulation Of B Cell Tolerance Induction Mammary Gland Morphogenesis Lymphoid Lineage Cell Migration Into Thymus Thymus Epithelium Morphogenesis Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Mesenchymal Cell Differentiation Regulation Of Epithelial To Mesenchymal Transition Skeletal System Morphogenesis Proepicardium Development	Acrosomal Vesicle Spermatid Development Magnesium Ion Binding Germ Cell Development Protein-containing Complex Binding Protein Phosphorylation Protein Serine Kinase Activity Protein Serine/threonine Kinase Activity Phosphorylation Male Gamete Generation Spermatogenesis Protein Kinase Activity Gamete Generation Kinase Activity Cell Development Developmental Process Involved In Reproduction ATP Binding Reproductive Process Phosphate-containing Compound Metabolic Process Protein Modification Process Nucleotide Binding Transferase Activity Protein Autophosphorylation Centriole Cell Differentiation Motile Cilium Cellular Developmental Process Protein Metabolic Process
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