INHBE and FST

Number of citations of the paper that reports this interaction (PMID 12242034)
5

Data Source:
HPRD (in vitro)

		INHBE	FST
Gene Name		inhibin, beta E	follistatin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space	Extracellular Region Nucleus Cytoplasm
	Molecular Function	Cytokine Activity Transforming Growth Factor Beta Receptor Binding Hormone Activity Growth Factor Activity	Signal Transducer Activity Protein Binding Heparan Sulfate Proteoglycan Binding Activin Binding
	Biological Process	Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Growth Regulation Of Apoptotic Process Regulation Of MAPK Cascade Cell Development SMAD Protein Signal Transduction	Negative Regulation Of Transcription From RNA Polymerase II Promoter Skeletal System Development Hematopoietic Progenitor Cell Differentiation Gamete Generation Pattern Specification Process Female Gonad Development BMP Signaling Pathway Hair Follicle Morphogenesis Negative Regulation Of Activin Receptor Signaling Pathway Odontogenesis Of Dentin-containing Tooth Keratinocyte Proliferation Negative Regulation Of Cell Differentiation Positive Regulation Of Hair Follicle Development
Pathways		Peptide hormone metabolism Glycoprotein hormones Peptide hormone biosynthesis	Antagonism of Activin by Follistatin Signaling by Activin
Drugs
Diseases
GWAS		Urate levels ( 23263486)
Protein-Protein Interactions		1 interactors: FST	9 interactors: BMP5 C8orf33 FN1 INHA INHBA INHBE MEST TK1 TXN
Entrez ID		83729	10468
HPRD ID		11047	00641
Ensembl ID		ENSG00000139269	ENSG00000134363
Uniprot IDs		P58166	P19883
PDB IDs			2B0U 2P6A 3HH2
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Activin Receptor Signaling Pathway Positive Regulation Of Hair Follicle Development Keratinocyte Proliferation Regulation Of Hair Follicle Development Regulation Of Activin Receptor Signaling Pathway Regulation Of Hair Cycle Positive Regulation Of Epidermis Development Hair Follicle Morphogenesis Epidermis Morphogenesis Skin Morphogenesis Regulation Of Epidermis Development BMP Signaling Pathway Epithelial Cell Proliferation Hair Follicle Development Hair Cycle Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Hair Cycle Odontogenesis Of Dentin-containing Tooth Female Gonad Development Development Of Primary Female Sexual Characteristics Odontogenesis Hematopoietic Progenitor Cell Differentiation Skin Development Gonad Development Development Of Primary Sexual Characteristics Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Epidermis Development Sex Differentiation	Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Pathway-restricted SMAD Protein Phosphorylation SMAD Protein Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Negative Regulation Of Follicle-stimulating Hormone Secretion Positive Regulation Of Follicle-stimulating Hormone Secretion Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Follicle-stimulating Hormone Secretion Positive Regulation Of Protein Phosphorylation Hemoglobin Biosynthetic Process Negative Regulation Of Gonadotropin Secretion Negative Regulation Of B Cell Differentiation Positive Regulation Of Phosphorylation Negative Regulation Of Interferon-gamma Biosynthetic Process Positive Regulation Of Protein Modification Process Negative Regulation Of Macrophage Differentiation Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Phosphorylation Hemoglobin Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Regulation Of Phosphorylation Male Sex Differentiation Regulation Of MAPK Cascade Positive Regulation Of Cellular Metabolic Process Regulation Of B Cell Differentiation Regulation Of Phosphorus Metabolic Process Regulation Of Cell Death Negative Regulation Of Interferon-gamma Production Endodermal Cell Differentiation Negative Regulation Of Cytokine Biosynthetic Process Negative Regulation Of B Cell Activation Sex Differentiation Regulation Of Intracellular Signal Transduction Anatomical Structure Development Negative Regulation Of Lymphocyte Differentiation Cell Development Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Myeloid Leukocyte Differentiation Endoderm Formation Positive Regulation Of Metabolic Process Negative Regulation Of Hormone Secretion Negative Regulation Of Immune System Process Response To Stimulus Developmental Process Ovarian Follicle Development Negative Regulation Of Transport Fetal Process Involved In Parturition Negative Regulation Of Myeloid Cell Differentiation
Tagcloud ?		aligned amenable avenues baz2a bioinformatic candidates cdk13 chem dapk1 digest dilution dst exosc3 hdms hierarchical kat2b kif20b linkages noninvasive pancreatic proteomics resectable silva smc1b spag5 synapt tryptic unsupervised urgent	activin anthropometric blocking consideration copyright correlate elisa eumenorrheic follicular follistatin gestation luteal menstrual nested periods permit phases postpartum preeclamptic pregnancy pregnant protected reserved rights sought subset throughout towards women
Tagcloud (Difference) ?		aligned amenable avenues baz2a bioinformatic candidates cdk13 chem dapk1 digest dilution dst exosc3 hdms hierarchical kat2b kif20b linkages noninvasive pancreatic proteomics resectable silva smc1b spag5 synapt tryptic unsupervised urgent	activin anthropometric blocking consideration copyright correlate elisa eumenorrheic follicular follistatin gestation luteal menstrual nested periods permit phases postpartum preeclamptic pregnancy pregnant protected reserved rights sought subset throughout towards women
Tagcloud (Intersection) ?