TMED8 and ADTRP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMED8	ADTRP
Description		transmembrane p24 trafficking protein family member 8	androgen dependent TFPI regulating protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Plasma Membrane Caveola Cell Surface Endomembrane System Membrane
	Molecular Function	Protein Binding	Protein Binding Hydrolase Activity
	Biological Process		Cell Migration Involved In Sprouting Angiogenesis Negative Regulation Of Leukocyte Migration Negative Regulation Of Extracellular Matrix Constituent Secretion Lipid Metabolic Process Positive Regulation Of Gene Expression Negative Regulation Of Blood Coagulation Long-chain Fatty Acid Catabolic Process Negative Regulation Of Protein Secretion Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Cellular Response To Steroid Hormone Stimulus Cellular Response To Oxidised Low-density Lipoprotein Particle Stimulus Negative Regulation Of Leukocyte Cell-cell Adhesion Negative Regulation Of Lymphocyte Migration
Pathways
Drugs
Diseases
GWAS			Apolipoprotein B levels ( 32203549) Body mass index ( 26426971) Daytime sleep phenotypes ( 27126917) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Refractive error ( 32231278) Simvastatin-induced myopathy ( 31220337) Social science traits (pleiotropy) (HIPO component 1) ( 30289880) Spatial processing ( 31596458) Thrombosis ( 26908601)
Interacting Genes		32 interacting genes: ADTRP AMIGO2 APOL2 ARL6IP1 C10orf67 CIAO2A CMTM5 CMTM6 CYB561D1 DEFB129 DERL1 DGAT2L6 EI24 H4C7 LAPTM4A MDK MMGT1 MRPL41 MRPS18B MTIF3 NDUFA12 REEP6 SERP2 STX8 SUSD3 TMEM115 TMEM121 TMEM218 TMEM254 TRAM1L1 UNC50 ZDHHC16	5 interacting genes: CMTM7 CREB3 S100B TMED8 VTN
Entrez ID		283578	84830
HPRD ID		18201	12836
Ensembl ID		ENSG00000100580	ENSG00000111863
Uniprot IDs		Q6PL24	Q96IZ2
PDB IDs
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Membrane	Glial Cell Differentiation Symbiont-containing Vacuole Smooth Muscle Cell-matrix Adhesion Positive Regulation Of Deacetylase Activity B-1a B Cell Differentiation Rough Endoplasmic Reticulum Lumen Alphav-beta3 Integrin-vitronectin Complex Response To Anesthetic Response To Methylmercury Sympathetic Neuron Projection Extension Peptidase Inhibitor Complex CCR1 Chemokine Receptor Binding Release From Viral Latency B-1 B Cell Differentiation Negative Regulation Of Skeletal Muscle Cell Differentiation
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