TMED8 and LAPTM4A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMED8	LAPTM4A
Description		transmembrane p24 trafficking protein family member 8	lysosomal protein transmembrane 4 alpha
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Lysosomal Membrane Golgi Apparatus Endomembrane System Membrane Late Endosome Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS			Major depressive disorder ( 21621269) Neurological blood protein biomarker levels ( 31320639)
Interacting Genes		32 interacting genes: ADTRP AMIGO2 APOL2 ARL6IP1 C10orf67 CIAO2A CMTM5 CMTM6 CYB561D1 DEFB129 DERL1 DGAT2L6 EI24 H4C7 LAPTM4A MDK MMGT1 MRPL41 MRPS18B MTIF3 NDUFA12 REEP6 SERP2 STX8 SUSD3 TMEM115 TMEM121 TMEM218 TMEM254 TRAM1L1 UNC50 ZDHHC16	9 interacting genes: FFAR2 GLP1R MTNR1A SLC22A1 SLC22A2 TMED8 TRIM55 TRIM63 TUBB3
Entrez ID		283578	9741
HPRD ID		18201	13959
Ensembl ID		ENSG00000100580	ENSG00000068697
Uniprot IDs		Q6PL24	Q15012 Q6IBP4
PDB IDs
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Membrane	Acetylcholine Transport Pyrimidine Nucleoside Transmembrane Transporter Activity Epinephrine Transport Spermidine Transmembrane Transport Putrescine Transport Spermidine Transmembrane Transporter Activity Putrescine Transmembrane Transporter Activity Acetylcholine Transmembrane Transporter Activity Spermidine Transport Thiamine Transmembrane Transporter Activity Thiamine Transport Quaternary Ammonium Group Transmembrane Transporter Activity Thiamine Transmembrane Transport Norepinephrine Uptake Xenobiotic Transport Across Blood-brain Barrier Toxin Transmembrane Transporter Activity Polyamine Transmembrane Transport Serotonin Uptake Norepinephrine Transport Prostaglandin Transmembrane Transporter Activity Monoamine Transmembrane Transporter Activity Organic Cation Transmembrane Transporter Activity Catecholamine Uptake Dopamine Uptake Azole Transmembrane Transport Serotonin Transport Quaternary Ammonium Group Transport Prostaglandin Transport Pyrimidine-containing Compound Transmembrane Transport Neurotransmitter Transmembrane Transporter Activity Vitamin Transmembrane Transport Organic Anion Transmembrane Transporter Activity Leukocyte Migration Involved In Inflammatory Response Dopamine Transport Neurotransmitter Reuptake Xenobiotic Transmembrane Transporter Activity Monoamine Transport Neurotransmitter Uptake Purine-containing Compound Transmembrane Transport Vitamin Transport Xenobiotic Transport Glucagon-like Peptide 1 Receptor Activity Basal Plasma Membrane Microtubule G Protein-coupled Receptor Activity Positive Regulation Of Acute Inflammatory Response To Non-antigenic Stimulus (R)-carnitine Transmembrane Transport (R)-carnitine Transmembrane Transporter Activity Organic Cation Transport Transport Across Blood-brain Barrier
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